C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ROS proto-oncogene 1 , receptor tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000047936 ROS1 9606 - 6:117288300-117425855 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368507 ROS1-002 117288300-117425855 protein_coding
  ENST00000368508 ROS1-001 117288300-117425855 protein_coding
  ENST00000403284 ROS1-003 117328420-117337340 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungENST00000368508
Transcript ID Lung
ENST00000368508 6.713±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005XO CIL_0005XO_0001 CGP 6:117265558-117425855

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002066 ISS columnar/cuboidal epithelial cell development
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007283 ISS spermatogenesis
GO:0008283 ISS cell proliferation
GO:0010629 IEA negative regulation of gene expression
GO:0010966 IEA regulation of phosphate transport
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0016049 IDA cell growth
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019903 IPI protein phosphatase binding
GO:0030154 ISS cell differentiation
GO:0032006 IDA regulation of TOR signaling
GO:0070372 ISS regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087197 ros1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) protein_coding Danio_rerio
ENSMUSG00000019893 Ros1 Ros1 proto-oncogene protein_coding Mus_musculus

Loading