C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ROS proto-oncogene 1 , receptor tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368508 ROS1-001 ENSG00000047936 9606 - 6:117288300-117425855 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungENST00000368508
Transcript ID Lung
ENST00000368508 6.713±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005XO CIL_0005XO_0001 CGP 6:117265558-117425855

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002066 ISS columnar/cuboidal epithelial cell development
GO:0004672 IEA protein kinase activity
GO:0004713 IDA:IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007283 ISS spermatogenesis
GO:0008283 ISS cell proliferation
GO:0010629 IEA negative regulation of gene expression
GO:0010966 IEA regulation of phosphate transport
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0016049 IDA cell growth
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019903 IPI protein phosphatase binding
GO:0030154 ISS cell differentiation
GO:0032006 IDA regulation of TOR signaling
GO:0070372 ISS regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020045 Ros1-001 protein_coding Mus_musculus 0 5005
ENSMUST00000117992 Ros1-002 protein_coding Mus_musculus 0 5000
ENSMUST00000177378 Ros1-004 nonsense_mediated_decay Mus_musculus 0 3530
ENSMUST00000175892 Ros1-003 nonsense_mediated_decay Mus_musculus 0 2656

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