C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Ros1 proto-oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019893 Ros1 10090 - 10:52045721-52195244 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020045 Ros1-001 52045926-52195244 protein_coding
  ENSMUST00000117992 Ros1-002 52046016-52194956 protein_coding
  ENSMUST00000175892 Ros1-003 52046016-52194956 nonsense_mediated_decay
  ENSMUST00000177378 Ros1-004 52045721-52194956 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020045ENSMUST00000117992ENSMUST00000175892ENSMUST00000177378
Transcript ID Adipose Bladder Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020045 N/A N/A N/A N/A N/A N/A N/A N/A 0.022±0.00 0.065±0.00
ENSMUST00000117992 0.049±0.00 0.002±0.00 N/A 0.085±0.00 0.016±0.01 0.144±0.02 0.029±0.02 0.011±0.00 N/A 0.079±0.05
ENSMUST00000175892 N/A N/A 0.029±0.00 0.056±0.00 0.002±0.00 0.014±0.00 0.039±0.03 0.011±0.00 0.006±0.00 0.081±0.00
ENSMUST00000177378 0.004±0.00 N/A N/A N/A 0.008±0.00 N/A 0.018±0.00 N/A 0.006±0.00 0.077±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005XO CIL_0005XO_0002 CGP 10:52022502-52195244

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002066 IMP columnar/cuboidal epithelial cell development
GO:0004713 ISS protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0007283 IMP spermatogenesis
GO:0008283 IDA cell proliferation
GO:0010629 IMP negative regulation of gene expression
GO:0010966 IMP regulation of phosphate transport
GO:0016021 IEA integral component of membrane
GO:0016049 ISS cell growth
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019903 IPI protein phosphatase binding
GO:0030154 IDA cell differentiation
GO:0032006 ISS regulation of TOR signaling
GO:0070372 IDA regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087197 ros1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) protein_coding Danio_rerio
ENSG00000047936 ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase protein_coding Homo_sapiens

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