C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dickkopf WNT signaling pathway inhibitor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000050165 DKK3 9606 - 11:11963106-12009769 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000326932 DKK3-001 11963106-12009370 protein_coding
  ENST00000396505 DKK3-004 11963106-12009082 protein_coding
  ENST00000525493 DKK3-002 11964391-12009769 protein_coding
  ENST00000525927 DKK3-012 11965873-11979916 processed_transcript
  ENST00000526218 DKK3-013 11978840-12009725 processed_transcript
  ENST00000527132 DKK3-003 11963106-12008630 processed_transcript
  ENST00000528188 DKK3-015 11964615-11994719 processed_transcript
  ENST00000529338 DKK3-017 11968443-12009137 protein_coding
  ENST00000530694 DKK3-005 12001675-12009737 processed_transcript
  ENST00000531309 DKK3-008 11998200-12002426 retained_intron
  ENST00000532372 DKK3-014 11965850-11968746 retained_intron
  ENST00000532873 DKK3-009 11965880-12008897 processed_transcript
  ENST00000533813 DKK3-010 11965935-12009211 protein_coding
  ENST00000533900 DKK3-006 12001904-12009212 processed_transcript
  ENST00000534479 DKK3-007 12001749-12009330 retained_intron
  ENST00000534511 DKK3-016 11966993-12008624 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000326932ENST00000396505ENST00000525493ENST00000527132
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000326932 3.610±0.00 5.863±0.00 N/A 139.310±116.71 6.327±5.06 17.170±16.31 32.072±30.92 8.918±8.66 1.432±0.00 12.096±8.58 3.415±0.00 22.292±16.28 23.231±2.93 22.168±12.81
ENST00000396505 N/A N/A N/A 6.394±0.00 1.044±0.00 N/A 3.153±0.00 N/A N/A 3.872±0.00 N/A N/A N/A N/A
ENST00000525493 N/A N/A 2.079±0.00 13.510±0.00 N/A N/A 3.132±0.00 N/A N/A N/A 1.643±0.00 N/A N/A N/A
ENST00000527132 3.258±0.00 11.773±0.00 N/A 63.041±38.73 2.672±0.00 6.633±5.33 3.059±0.00 3.599±3.10 5.234±3.67 N/A 0.862±0.00 22.580±0.00 25.344±0.00 16.409±0.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001HU CIL_0001HU_0002 CGP 11:11841423-12009769
CIL_0008T3 CIL_0008T3_0001 VISTA 11:11882278-12483702
CIL_0008YS CIL_0008YS_0001 VISTA 11:11899653-12500760
CIL_0007SQ CIL_0007SQ_0001 VISTA 11:11959946-12561868
CIL_0004J2 CIL_0004J2_0001 CGP 11:11963106-12263789

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005576 IEA extracellular region
GO:0005615 TAS extracellular space
GO:0007275 IEA multicellular organismal development
GO:0009653 TAS anatomical structure morphogenesis
GO:0016055 IEA Wnt signaling pathway
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0030325 IEP adrenal gland development
GO:0032348 IDA negative regulation of aldosterone biosynthetic process
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:2000065 IDA negative regulation of cortisol biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070683 dkk3b dickkopf homolog 3b (Xenopus laevis) protein_coding Danio_rerio
ENSDARG00000077630 dkk3a dickkopf homolog 3a (Xenopus laevis) protein_coding Danio_rerio
ENSMUSG00000030772 Dkk3 dickkopf homolog 3 (Xenopus laevis) protein_coding Mus_musculus

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