C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: anaphase promoting complex subunit 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000053900 ANAPC4 9606 + 4:25377213-25418498 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000315368 ANAPC4-001 25377213-25418498 protein_coding
  ENST00000503805 ANAPC4-010 25394758-25409769 retained_intron
  ENST00000504256 ANAPC4-003 25405601-25418498 retained_intron
  ENST00000505080 ANAPC4-008 25377315-25390183 nonsense_mediated_decay
  ENST00000505842 ANAPC4-011 25396719-25413871 retained_intron
  ENST00000505991 ANAPC4-006 25377320-25388854 protein_coding
  ENST00000506973 ANAPC4-005 25415152-25418497 retained_intron
  ENST00000507809 ANAPC4-007 25377357-25380608 retained_intron
  ENST00000507925 ANAPC4-009 25393861-25395420 retained_intron
  ENST00000510092 ANAPC4-002 25377293-25418489 protein_coding
  ENST00000515848 ANAPC4-004 25412918-25418261 retained_intron

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000315368ENST00000504256ENST00000505991ENST00000510092ENST00000515848
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000315368 1.969±0.00 2.556±0.00 N/A 1.918±0.66 5.526±0.00 1.064±0.00 0.930±0.00 N/A 2.031±0.30 1.769±0.00 N/A 8.157±0.00 3.060±0.47 4.659±0.00
ENST00000504256 N/A 0.967±0.00 N/A N/A N/A N/A N/A N/A N/A 0.188±0.00 N/A 1.136±0.20 N/A N/A
ENST00000505991 N/A N/A 4.606±0.00 N/A N/A 5.036±0.00 2.243±0.00 N/A N/A N/A 2.374±0.00 N/A N/A N/A
ENST00000510092 1.506±0.00 1.204±0.00 1.224±0.00 1.168±0.00 2.178±0.00 1.784±0.34 1.051±0.57 2.456±1.89 2.593±0.00 3.344±0.00 1.875±0.00 2.627±0.71 3.380±0.00 1.729±0.77
ENST00000515848 N/A N/A N/A 0.821±0.00 2.112±0.00 1.320±0.00 N/A 1.445±0.00 3.368±0.00 1.158±0.68 N/A N/A N/A 2.366±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002F9 CIL_0002F9_0001 CGP 4:25312785-25418498
CIL_0002FA CIL_0002FA_0001 CGP 4:25377213-25678748

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0004842 TAS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005680 IEA:IDA anaphase-promoting complex
GO:0005829 TAS cytosol
GO:0007067 IEA mitotic nuclear division
GO:0007094 TAS mitotic spindle assembly checkpoint
GO:0019903 IPI protein phosphatase binding
GO:0030071 IEA regulation of mitotic metaphase/anaphase transition
GO:0031145 IEA:TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070979 IDA protein K11-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032237 anapc4 anaphase promoting complex subunit 4 protein_coding Danio_rerio
ENSMUSG00000029176 Anapc4 anaphase promoting complex subunit 4 protein_coding Mus_musculus

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