C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Sec61 alpha 1 subunit (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000058262 SEC61A1 9606 + 3:128051641-128071683 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000243253 SEC61A1-001 128052369-128071682 protein_coding
  ENST00000424880 SEC61A1-003 128052759-128071677 protein_coding
  ENST00000464451 SEC61A1-002 128051641-128069839 protein_coding
  ENST00000481210 SEC61A1-005 128052426-128060211 protein_coding
  ENST00000483956 SEC61A1-004 128064899-128071683 processed_transcript
  ENST00000491668 SEC61A1-006 128052489-128055750 retained_intron
  ENST00000498837 SEC61A1-007 128067781-128069751 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000243253ENST00000424880ENST00000464451
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000243253 72.717±0.00 54.498±0.00 4.316±0.00 5.380±1.37 11.119±1.69 20.845±14.27 9.545±6.24 22.994±1.03 39.123±35.56 15.411±9.34 13.575±11.56 45.325±29.54 105.308±13.79 23.907±16.14
ENST00000424880 N/A N/A 2.196±0.00 N/A 3.945±0.00 7.404±0.00 N/A N/A N/A 7.285±0.00 N/A 24.833±0.00 31.073±0.00 10.864±0.00
ENST00000464451 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.597±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005791 IEA rough endoplasmic reticulum
GO:0006614 IMP SRP-dependent cotranslational protein targeting to membrane
GO:0006620 IMP posttranslational protein targeting to membrane
GO:0007029 IMP endoplasmic reticulum organization
GO:0015031 IEA protein transport
GO:0016020 IEA:IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016049 IMP cell growth
GO:0030176 ISS integral component of endoplasmic reticulum membrane
GO:0034341 IEA response to interferon-gamma
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043022 ISS ribosome binding
GO:0045047 ISS protein targeting to ER

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005675 sec61al2 Sec61 alpha like 2 protein_coding Danio_rerio
ENSDARG00000021669 sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000030082 Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) protein_coding Mus_musculus

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