C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: engulfment and cell motility 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000062598 ELMO2 9606 - 20:46366049-46432985 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290246 ELMO2-001 46366049-46406617 protein_coding
  ENST00000352077 ELMO2-004 46367360-46394482 protein_coding
  ENST00000372176 ELMO2-003 46366050-46406559 protein_coding
  ENST00000396391 ELMO2-201 46366055-46406632 protein_coding
  ENST00000425546 ELMO2-005 46372835-46386164 protein_coding
  ENST00000450812 ELMO2-002 46375286-46406604 protein_coding
  ENST00000452857 ELMO2-007 46366054-46373515 protein_coding
  ENST00000460474 ELMO2-012 46383468-46406615 processed_transcript
  ENST00000462491 ELMO2-015 46373241-46386164 processed_transcript
  ENST00000462593 ELMO2-013 46387505-46394437 processed_transcript
  ENST00000464448 ELMO2-017 46370443-46373495 processed_transcript
  ENST00000467800 ELMO2-006 46366050-46375771 nonsense_mediated_decay
  ENST00000469801 ELMO2-011 46383416-46406615 processed_transcript
  ENST00000480042 ELMO2-014 46379919-46386165 processed_transcript
  ENST00000481852 ELMO2-016 46374351-46376967 processed_transcript
  ENST00000487583 ELMO2-008 46387427-46432985 processed_transcript
  ENST00000488853 ELMO2-010 46374438-46406599 processed_transcript
  ENST00000497412 ELMO2-009 46386124-46406624 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290246ENST00000352077ENST00000372176ENST00000396391ENST00000425546ENST00000452857ENST00000462491ENST00000462593ENST00000467800ENST00000480042ENST00000488853
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290246 2.296±0.00 N/A N/A 3.476±0.00 N/A N/A 3.902±0.00 1.489±0.00 0.674±0.00 N/A 1.775±0.00 2.753±1.70 2.767±0.46 6.295±0.98
ENST00000352077 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.821±0.00 N/A
ENST00000372176 1.657±0.00 N/A N/A 3.033±0.00 N/A 0.603±0.00 N/A N/A N/A 1.179±0.00 N/A 1.420±0.00 N/A N/A
ENST00000396391 N/A 2.008±0.00 N/A 3.037±0.00 N/A 2.337±0.00 2.355±0.00 3.296±0.00 N/A 2.506±0.00 N/A 4.122±0.37 3.195±0.23 6.699±3.33
ENST00000425546 N/A N/A N/A N/A N/A N/A N/A 0.457±0.00 N/A N/A N/A N/A N/A N/A
ENST00000452857 2.237±0.00 6.192±0.00 N/A 4.335±1.65 2.133±0.50 2.603±1.53 N/A 2.936±2.29 2.181±0.00 2.912±0.00 3.096±2.45 4.890±2.83 2.531±0.52 10.822±0.00
ENST00000462491 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.422±0.00 N/A N/A N/A N/A
ENST00000462593 N/A N/A N/A N/A N/A N/A N/A 1.346±0.00 N/A N/A N/A N/A N/A N/A
ENST00000467800 N/A N/A N/A N/A N/A 0.596±0.00 N/A N/A 1.163±0.00 0.748±0.30 N/A 0.462±0.00 N/A N/A
ENST00000480042 N/A N/A 2.800±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000488853 N/A N/A N/A N/A N/A 0.775±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006G4 CIL_0006G4_0001 CGP 20:46345980-46432985

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0005856 IEA cytoskeleton
GO:0006909 IEA phagocytosis
GO:0006915 IEA apoptotic process
GO:0016020 IDA membrane
GO:0017124 IEA SH3 domain binding
GO:0030971 IPI receptor tyrosine kinase binding
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS innate immune response
GO:0060326 IMP cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063527 ELMO2 engulfment and cell motility 2 protein_coding Danio_rerio
ENSMUSG00000017670 Elmo2 engulfment and cell motility 2 protein_coding Mus_musculus

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