C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase N2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000065243 PKN2 9606 + 1:88684222-88836255 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316005 PKN2-002 88684222-88806268 protein_coding
  ENST00000370505 PKN2-201 88684551-88806201 protein_coding
  ENST00000370513 PKN2-202 88684573-88833519 protein_coding
  ENST00000370521 PKN2-001 88684222-88836255 protein_coding
  ENST00000436111 PKN2-003 88771455-88804894 protein_coding
  ENST00000449189 PKN2-004 88824346-88829167 protein_coding
  ENST00000495119 PKN2-005 88832929-88833431 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370505ENST00000370513ENST00000370521ENST00000436111
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370505 N/A N/A N/A 1.544±0.00 3.957±0.00 3.284±0.00 N/A 1.366±0.00 N/A N/A N/A N/A N/A N/A
ENST00000370513 4.399±0.00 1.526±0.00 3.708±0.00 2.014±0.22 5.044±0.75 4.435±1.08 3.238±0.40 4.198±0.00 4.369±0.00 3.100±0.78 1.311±0.41 4.246±0.44 3.308±2.16 3.981±1.11
ENST00000370521 2.525±0.00 1.001±0.00 2.620±0.00 0.944±0.53 1.572±0.18 2.180±1.09 1.219±0.28 1.065±0.23 2.456±1.11 2.652±1.66 0.573±0.10 4.328±1.89 2.543±0.41 1.624±0.17
ENST00000436111 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.601±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RA CIL_0008RA_0001 VISTA 1:88110048-88711509
CIL_0009B7 CIL_0009B7_0001 VISTA 1:88161113-88762825

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004697 IEA protein kinase C activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IDA:IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007049 IEA cell cycle
GO:0007155 IEA cell adhesion
GO:0007165 IEA signal transduction
GO:0010631 IDA epithelial cell migration
GO:0016020 IEA membrane
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030027 IDA lamellipodium
GO:0030496 IDA midbody
GO:0032154 IDA cleavage furrow
GO:0032467 IMP positive regulation of cytokinesis
GO:0042826 IDA histone deacetylase binding
GO:0043296 IDA apical junction complex
GO:0043297 IMP apical junction assembly
GO:0044822 IDA poly(A) RNA binding
GO:0045111 IDA intermediate filament cytoskeleton
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0051301 IEA cell division
GO:2000145 IMP regulation of cell motility

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006705 pkn2 protein kinase N2 protein_coding Danio_rerio
ENSDARG00000036707 PKN2 (2 of 2) protein kinase N2 protein_coding Danio_rerio
ENSMUSG00000004591 Pkn2 protein kinase N2 protein_coding Mus_musculus

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