C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: claudin 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000066405 CLDN18 9606 + 3:137998735-138033655 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000183605 CLDN18-002 138010000-138033649 protein_coding
  ENST00000343735 CLDN18-001 137998735-138033655 protein_coding
  ENST00000479660 CLDN18-003 138010216-138032502 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000183605ENST00000343735ENST00000479660
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000183605 N/A N/A N/A N/A N/A N/A 0.016±0.00 0.007±0.00 27.895±10.12 N/A N/A 0.512±0.20
ENST00000343735 0.035±0.00 N/A 0.040±0.03 0.025±0.00 N/A 0.015±0.00 N/A N/A 7.852±0.00 3.614±2.39 0.038±0.01 N/A
ENST00000479660 0.092±0.00 0.100±0.00 0.031±0.00 0.054±0.00 0.096±0.00 0.117±0.00 0.157±0.00 0.003±0.00 N/A 0.071±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YL CIL_0007YL_0001 VISTA 3:137620069-138221266

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005886 IEA plasma membrane
GO:0005923 ISS tight junction
GO:0016021 IEA integral component of membrane
GO:0016338 ISS calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0034329 TAS cell junction assembly
GO:0042802 ISS identical protein binding
GO:0045216 TAS cell-cell junction organization
GO:0070830 TAS tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079368 CLDN18 claudin 18 protein_coding Danio_rerio
ENSMUSG00000032473 Cldn18 claudin 18 protein_coding Mus_musculus

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