C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor binding to IGHM enhancer 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000068323 TFE3 9606 - X:49028726-49043486 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000315869 TFE3-001 49028731-49043486 protein_coding
  ENST00000481606 TFE3-002 49037739-49038259 processed_transcript
  ENST00000487451 TFE3-006 49031397-49039803 processed_transcript
  ENST00000493583 TFE3-004 49028726-49043410 nonsense_mediated_decay
  ENST00000495940 TFE3-003 49030515-49032067 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000315869ENST00000481606ENST00000487451ENST00000493583
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000315869 14.406±0.00 5.199±0.00 7.270±4.35 11.051±0.00 6.047±4.87 2.922±2.25 6.827±0.00 2.769±0.23 11.658±10.60 3.319±1.38 10.437±12.15 9.138±0.58 4.998±0.00
ENST00000481606 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.302±0.00 N/A N/A
ENST00000487451 N/A N/A 1.592±0.00 2.046±0.00 0.716±0.00 N/A 2.180±0.00 N/A N/A N/A N/A N/A N/A
ENST00000493583 25.779±0.00 13.771±0.00 4.840±4.40 24.645±24.34 16.795±0.00 4.197±0.00 11.373±0.00 3.692±0.00 19.122±0.00 6.129±0.00 9.189±4.81 7.150±2.68 9.106±5.26

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006959 ISS humoral immune response
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045670 IEA regulation of osteoclast differentiation
GO:0045785 IMP positive regulation of cell adhesion
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004729 tfe3a transcription factor binding to IGHM enhancer 3a protein_coding Danio_rerio
ENSDARG00000019457 tfe3b transcription factor binding to IGHM enhancer 3b protein_coding Danio_rerio
ENSMUSG00000000134 Tfe3 transcription factor E3 protein_coding Mus_musculus

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