C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acyl-CoA synthetase long-chain family member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000068366 ACSL4 9606 - X:109624244-109733403 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340800 ACSL4-201 109641337-109733392 protein_coding
  ENST00000348502 ACSL4-001 109641337-109733403 protein_coding
  ENST00000439581 ACSL4-012 109624244-109634686 processed_transcript
  ENST00000469796 ACSL4-003 109641337-109733302 protein_coding
  ENST00000469857 ACSL4-002 109683325-109733231 protein_coding
  ENST00000502391 ACSL4-007 109682813-109733325 protein_coding
  ENST00000504383 ACSL4-005 109695651-109733275 processed_transcript
  ENST00000504980 ACSL4-009 109682869-109733213 protein_coding
  ENST00000505075 ACSL4-011 109629350-109659513 processed_transcript
  ENST00000505855 ACSL4-008 109681319-109692147 protein_coding
  ENST00000508092 ACSL4-006 109682864-109733325 protein_coding
  ENST00000514500 ACSL4-010 109644026-109669109 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000348502ENST00000469796
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000348502 27.531±0.00 8.446±0.00 5.986±0.00 4.109±2.46 8.598±6.35 17.298±0.00 5.129±2.15 17.411±0.00 4.134±2.41 17.327±15.00 26.294±25.04 6.896±1.04 5.661±2.41 10.646±1.65
ENST00000469796 N/A N/A 1.873±0.00 5.382±2.39 N/A 3.242±0.00 N/A N/A N/A N/A N/A 2.097±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007A1 CIL_0007A1_0001 CGP X:109535781-109625172
CIL_00068B CIL_00068B_0001 CGP X:109623700-109733403
CIL_00079Z CIL_00079Z_0001 CGP X:109624244-110182734

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001676 IEA long-chain fatty acid metabolic process
GO:0003824 IEA catalytic activity
GO:0004467 IDA long-chain fatty acid-CoA ligase activity
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0005777 IEA peroxisome
GO:0005783 IEA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005811 IDA lipid particle
GO:0006629 IDA lipid metabolic process
GO:0006641 IEA triglyceride metabolic process
GO:0007584 IEA response to nutrient
GO:0008152 IEA metabolic process
GO:0008610 IDA lipid biosynthetic process
GO:0015908 IEA fatty acid transport
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019432 TAS triglyceride biosynthetic process
GO:0030182 IEA neuron differentiation
GO:0030307 IDA positive regulation of cell growth
GO:0031957 IMP very long-chain fatty acid-CoA ligase activity
GO:0031966 IEA mitochondrial membrane
GO:0032307 IDA negative regulation of prostaglandin secretion
GO:0035338 TAS long-chain fatty-acyl-CoA biosynthetic process
GO:0043025 IEA neuronal cell body
GO:0044233 IDA ER-mitochondrion membrane contact site
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0047676 IDA arachidonate-CoA ligase activity
GO:0060136 IEA embryonic process involved in female pregnancy
GO:0060996 IEA dendritic spine development
GO:0070062 IDA extracellular vesicular exosome
GO:0070672 IEA response to interleukin-15

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004078 acsl4a acyl-CoA synthetase long-chain family member 4a protein_coding Danio_rerio
ENSDARG00000010752 acsl4l acyl-CoA synthetase long-chain family member 4, like protein_coding Danio_rerio
ENSMUSG00000031278 Acsl4 acyl-CoA synthetase long-chain family member 4 protein_coding Mus_musculus

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