C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: acyl-CoA synthetase long-chain family member 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000348502 ACSL4-001 ENSG00000068366 9606 - X:109641337-109733403 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000348502
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000348502 27.531±0.00 8.446±0.00 5.986±0.00 4.109±2.46 8.598±6.35 17.298±0.00 5.129±2.15 17.411±0.00 4.134±2.41 17.327±15.00 26.294±25.04 6.896±1.04 5.661±2.41 10.646±1.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007A1 CIL_0007A1_0001 CGP X:109535781-109625172
CIL_00068B CIL_00068B_0001 CGP X:109623700-109733403
CIL_00079Z CIL_00079Z_0001 CGP X:109624244-110182734

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001676 IEA long-chain fatty acid metabolic process
GO:0003824 IEA catalytic activity
GO:0004467 IDA long-chain fatty acid-CoA ligase activity
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005741 IEA mitochondrial outer membrane
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005811 IDA lipid particle
GO:0006629 IDA lipid metabolic process
GO:0008152 IEA metabolic process
GO:0008610 IDA lipid biosynthetic process
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019432 TAS triglyceride biosynthetic process
GO:0030307 IDA positive regulation of cell growth
GO:0031957 IMP very long-chain fatty acid-CoA ligase activity
GO:0032307 IDA negative regulation of prostaglandin secretion
GO:0035338 TAS long-chain fatty-acyl-CoA biosynthetic process
GO:0044233 IDA ER-mitochondrion membrane contact site
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0047676 IDA arachidonate-CoA ligase activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112903 Acsl4-003 protein_coding Mus_musculus 0 3262
ENSMUST00000033634 Acsl4-001 protein_coding Mus_musculus 0 3249
ENSMUST00000112904 Acsl4-002 protein_coding Mus_musculus 0 3249
ENSMUST00000112907 Acsl4-004 protein_coding Mus_musculus 0 3249
ENSMUST00000140520 Acsl4-005 processed_transcript Mus_musculus 0.000000000000009 88

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