C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acyl-CoA synthetase long-chain family member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031278 Acsl4 10090 - X:142317993-142390535 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033634 Acsl4-001 142317993-142390535 protein_coding
  ENSMUST00000112903 Acsl4-003 142317993-142390504 protein_coding
  ENSMUST00000112904 Acsl4-002 142317993-142390504 protein_coding
  ENSMUST00000112907 Acsl4-004 142317993-142390344 protein_coding
  ENSMUST00000140520 Acsl4-005 142320671-142328025 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033634ENSMUST00000112903ENSMUST00000112904ENSMUST00000112907
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033634 1.430±0.62 57.692±14.64 1.524±0.15 2.813±0.38 1.481±0.67 0.832±0.18 0.469±0.08 0.814±0.12 0.857±0.14 3.185±0.57 N/A 6.174±4.70 N/A 0.847±0.22
ENSMUST00000112903 0.843±0.32 11.035±1.83 0.966±0.02 8.398±0.00 1.090±0.41 0.462±0.06 1.209±0.13 2.081±1.00 1.844±1.08 5.998±1.36 1.003±0.31 6.762±4.53 5.355±3.43 1.075±0.90
ENSMUST00000112904 2.744±0.61 N/A 3.885±0.18 N/A 2.423±0.93 1.720±0.51 0.624±0.33 4.107±1.06 5.238±1.26 11.629±2.98 3.418±0.99 12.880±7.86 8.020±2.95 0.722±0.19
ENSMUST00000112907 N/A N/A N/A 1.059±0.43 0.963±0.32 1.212±0.00 0.366±0.20 N/A N/A 3.637±0.00 N/A 4.625±0.36 N/A 0.476±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00068B CIL_00068B_0002 CGP X:142304752-142390535
CIL_00079Z CIL_00079Z_0002 CGP X:142317993-142843494

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001676 IEA long-chain fatty acid metabolic process
GO:0004467 ISA long-chain fatty acid-CoA ligase activity
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0005777 IEA peroxisome
GO:0005783 IEA endoplasmic reticulum
GO:0005811 IEA lipid particle
GO:0006629 IEA lipid metabolic process
GO:0006641 IEA triglyceride metabolic process
GO:0007584 IEA response to nutrient
GO:0008610 IEA lipid biosynthetic process
GO:0015908 IEA fatty acid transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019217 TAS regulation of fatty acid metabolic process
GO:0030182 IMP neuron differentiation
GO:0030307 IEA positive regulation of cell growth
GO:0031957 IEA very long-chain fatty acid-CoA ligase activity
GO:0031966 IEA mitochondrial membrane
GO:0032307 IEA negative regulation of prostaglandin secretion
GO:0043025 IEA neuronal cell body
GO:0044233 IEA ER-mitochondrion membrane contact site
GO:0047676 IEA arachidonate-CoA ligase activity
GO:0060136 IMP embryonic process involved in female pregnancy
GO:0060996 IEA dendritic spine development
GO:0070062 IEA extracellular vesicular exosome
GO:0070672 IEA response to interleukin-15

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004078 acsl4a acyl-CoA synthetase long-chain family member 4a protein_coding Danio_rerio
ENSDARG00000010752 acsl4l acyl-CoA synthetase long-chain family member 4, like protein_coding Danio_rerio
ENSG00000068366 ACSL4 acyl-CoA synthetase long-chain family member 4 protein_coding Homo_sapiens

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