C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072135 PTPN18 9606 + 2:130356007-130375409 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000175756 PTPN18-001 130356007-130375409 protein_coding
  ENST00000347849 PTPN18-002 130356045-130374571 protein_coding
  ENST00000409022 PTPN18-003 130370089-130374866 protein_coding
  ENST00000420717 PTPN18-013 130358864-130362430 processed_transcript
  ENST00000428843 PTPN18-006 130356066-130370188 nonsense_mediated_decay
  ENST00000460992 PTPN18-008 130359177-130359661 retained_intron
  ENST00000462321 PTPN18-004 130372608-130374533 retained_intron
  ENST00000462996 PTPN18-011 130370310-130372444 retained_intron
  ENST00000464576 PTPN18-015 130370433-130370917 retained_intron
  ENST00000479295 PTPN18-014 130358950-130359921 retained_intron
  ENST00000481492 PTPN18-012 130371998-130373989 retained_intron
  ENST00000483617 PTPN18-007 130358893-130370427 retained_intron
  ENST00000489215 PTPN18-005 130356055-130370229 retained_intron
  ENST00000490137 PTPN18-016 130370669-130371313 retained_intron
  ENST00000490812 PTPN18-010 130370128-130372453 retained_intron
  ENST00000495400 PTPN18-009 130368897-130370597 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000175756ENST00000347849ENST00000462321ENST00000479295ENST00000481492ENST00000483617ENST00000490812
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000175756 4.217±0.00 N/A N/A 0.883±0.00 2.208±0.00 0.140±0.00 2.847±1.27 3.020±0.00 N/A N/A 4.825±3.20 6.682±1.03 1.824±0.00
ENST00000347849 N/A N/A N/A N/A 2.420±0.00 N/A N/A N/A N/A 1.282±0.00 3.770±0.00 N/A N/A
ENST00000462321 9.082±0.00 N/A 1.797±0.00 1.234±0.00 2.254±0.00 N/A N/A N/A 1.500±0.00 N/A 1.062±0.00 N/A 1.391±0.00
ENST00000479295 N/A N/A N/A N/A N/A 0.754±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000481492 N/A 3.810±0.00 3.969±0.00 2.811±0.00 4.730±0.00 0.396±0.00 1.372±0.00 2.445±0.00 1.790±0.00 1.124±0.00 13.595±11.85 14.487±0.00 4.992±0.00
ENST00000483617 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.388±0.00 N/A N/A N/A
ENST00000490812 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.658±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001J6 CIL_0001J6_0001 CGP 2:130342225-130375409

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0004726 IEA non-membrane spanning protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006470 TAS:IEA protein dephosphorylation
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006308 ptpn18 protein tyrosine phosphatase, non-receptor type 18 protein_coding Danio_rerio
ENSMUSG00000026126 Ptpn18 protein tyrosine phosphatase, non-receptor type 18 protein_coding Mus_musculus

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