C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphodiesterase 8A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000073417 PDE8A 9606 + 15:84980440-85139145 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310298 PDE8A-001 84980440-85139145 protein_coding
  ENST00000339708 PDE8A-002 84981981-85138032 protein_coding
  ENST00000394553 PDE8A-201 84981974-85139136 protein_coding
  ENST00000478717 PDE8A-003 84981981-85138032 nonsense_mediated_decay
  ENST00000485596 PDE8A-004 84981981-85138032 nonsense_mediated_decay
  ENST00000557819 PDE8A-010 85067028-85113400 processed_transcript
  ENST00000557954 PDE8A-012 85099757-85113956 retained_intron
  ENST00000557957 PDE8A-005 84980513-85139142 protein_coding
  ENST00000558543 PDE8A-011 85097803-85114038 retained_intron
  ENST00000559086 PDE8A-009 84982226-85109130 nonsense_mediated_decay
  ENST00000559742 PDE8A-006 84981981-85138032 nonsense_mediated_decay
  ENST00000560333 PDE8A-014 85115769-85117832 retained_intron
  ENST00000560789 PDE8A-007 85062497-85138607 retained_intron
  ENST00000561024 PDE8A-008 85120191-85139142 retained_intron
  ENST00000561105 PDE8A-015 85099979-85100258 retained_intron
  ENST00000561374 PDE8A-013 85115256-85116309 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310298ENST00000339708ENST00000394553ENST00000478717ENST00000485596ENST00000557957ENST00000559742ENST00000560789ENST00000561024
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310298 N/A N/A N/A N/A N/A 0.708±0.00 0.784±0.00 4.786±0.00 N/A N/A N/A 0.950±0.00 0.528±0.00 N/A
ENST00000339708 2.232±0.00 N/A N/A N/A N/A 1.357±0.00 N/A N/A N/A 1.526±0.00 N/A N/A N/A N/A
ENST00000394553 3.320±0.00 1.467±0.00 N/A 1.987±0.02 3.052±1.97 1.702±0.70 0.701±0.20 3.589±0.00 2.823±1.18 2.577±0.00 1.022±0.00 1.973±0.86 2.524±0.19 2.502±0.00
ENST00000478717 N/A 1.530±0.00 2.201±0.00 0.956±0.00 N/A 1.695±0.00 N/A N/A N/A N/A N/A 3.733±0.00 1.088±0.00 N/A
ENST00000485596 1.894±0.00 N/A N/A 3.111±0.00 0.982±0.00 1.122±0.00 N/A N/A N/A N/A N/A 4.167±0.00 1.968±0.00 N/A
ENST00000557957 1.375±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.521±0.25 N/A 3.632±0.00
ENST00000559742 N/A N/A N/A 2.613±0.00 N/A N/A 0.934±0.42 N/A N/A 1.341±0.00 0.862±0.00 N/A N/A 3.613±0.00
ENST00000560789 N/A N/A N/A N/A 0.896±0.00 N/A N/A N/A 0.851±0.00 N/A N/A N/A N/A N/A
ENST00000561024 N/A N/A 1.612±0.00 2.463±1.12 1.747±0.00 2.109±0.75 N/A 2.158±0.30 N/A N/A 0.932±0.00 1.803±0.70 N/A 2.398±0.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000M0 CIL_0000M0_0001 CGP 15:84884654-85139145

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000160 IEA phosphorelay signal transduction system
GO:0004114 NAS:IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 IEA 3',5'-cyclic-AMP phosphodiesterase activity
GO:0004871 IEA signal transducer activity
GO:0005829 TAS cytosol
GO:0006198 IEA cAMP catabolic process
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0009187 NAS cyclic nucleotide metabolic process
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088905 pde8a phosphodiesterase 8A protein_coding Danio_rerio
ENSMUSG00000025584 Pde8a phosphodiesterase 8A protein_coding Mus_musculus

Loading