C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor susceptibility 101
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000074319 TSG101 9606 - 11:18468336-18527232 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000251968 TSG101-001 18480311-18527232 protein_coding
  ENST00000438874 TSG101-008 18502543-18526899 processed_transcript
  ENST00000535077 TSG101-005 18506866-18526920 processed_transcript
  ENST00000536719 TSG101-002 18468336-18526951 protein_coding
  ENST00000540555 TSG101-007 18481491-18484061 retained_intron
  ENST00000542488 TSG101-003 18506857-18526821 processed_transcript
  ENST00000543054 TSG101-011 18483936-18514850 retained_intron
  ENST00000543087 TSG101-004 18490830-18514843 processed_transcript
  ENST00000544804 TSG101-009 18502485-18526881 processed_transcript
  ENST00000545247 TSG101-006 18483836-18526913 retained_intron
  ENST00000580814 TSG101-016 18469031-18481731 nonsense_mediated_decay
  ENST00000584526 TSG101-015 18475219-18481771 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000251968ENST00000540555ENST00000543054ENST00000545247ENST00000580814
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000251968 20.752±0.00 16.059±0.00 2.685±0.00 13.348±7.41 13.010±9.08 12.081±6.60 12.606±10.98 17.961±16.07 7.737±3.75 9.178±6.35 19.153±0.00 19.585±7.60 27.315±13.09 30.625±16.21
ENST00000540555 N/A N/A N/A N/A 3.939±0.00 10.980±0.00 N/A 2.253±0.00 N/A 14.726±0.00 7.307±0.00 26.074±15.06 41.259±0.00 50.407±0.00
ENST00000543054 N/A N/A N/A 9.247±0.00 N/A N/A N/A N/A N/A 6.475±0.00 11.062±1.75 11.501±0.00 12.788±0.00 N/A
ENST00000545247 N/A N/A N/A N/A N/A N/A 1.719±0.00 N/A N/A N/A 2.591±0.00 3.412±0.00 N/A N/A
ENST00000580814 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.597±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044S CIL_00044S_0001 CGP 11:18468336-18588747

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000813 IDA ESCRT I complex
GO:0001558 IEA regulation of cell growth
GO:0003677 TAS DNA binding
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005730 IDA nucleolus
GO:0005737 ISS cytoplasm
GO:0005769 IDA early endosome
GO:0005770 IMP late endosome
GO:0005771 TAS multivesicular body
GO:0005886 IDA plasma membrane
GO:0006464 IEA cellular protein modification process
GO:0007050 IEA cell cycle arrest
GO:0008285 IEA negative regulation of cell proliferation
GO:0010008 TAS endosome membrane
GO:0015031 IEA protein transport
GO:0016032 TAS viral process
GO:0016197 TAS endosomal transport
GO:0019058 TAS viral life cycle
GO:0019068 TAS virion assembly
GO:0019082 TAS viral protein processing
GO:0030154 IEA cell differentiation
GO:0030216 IEA keratinocyte differentiation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0042803 IPI protein homodimerization activity
GO:0043130 TAS ubiquitin binding
GO:0043162 IDA ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046755 ISS viral budding
GO:0048306 IPI calcium-dependent protein binding
GO:0051301 IEA cell division
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0075733 TAS intracellular transport of virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011897 TSG101 (1 of 5) tumor susceptibility 101 protein_coding Danio_rerio
ENSDARG00000040854 tsg101a tumor susceptibility gene 101a protein_coding Danio_rerio
ENSDARG00000086195 TSG101 (4 of 5) tumor susceptibility 101 protein_coding Danio_rerio
ENSMUSG00000014402 Tsg101 tumor susceptibility gene 101 protein_coding Mus_musculus

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