C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 10-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000074964 ARHGEF10L 9606 + 1:17539835-17697874 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000167825 ARHGEF10L-005 17626007-17697868 nonsense_mediated_decay
  ENST00000361221 ARHGEF10L-001 17539835-17697869 protein_coding
  ENST00000375408 ARHGEF10L-002 17618316-17697868 protein_coding
  ENST00000375415 ARHGEF10L-003 17580553-17697649 protein_coding
  ENST00000466782 ARHGEF10L-009 17639753-17654665 processed_transcript
  ENST00000469726 ARHGEF10L-004 17615088-17697860 processed_transcript
  ENST00000482359 ARHGEF10L-008 17634257-17638003 processed_transcript
  ENST00000482892 ARHGEF10L-007 17602171-17604882 processed_transcript
  ENST00000495593 ARHGEF10L-006 17694047-17697874 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000167825ENST00000361221ENST00000375408ENST00000375415ENST00000469726ENST00000495593
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000167825 N/A N/A N/A N/A 1.229±0.00 0.646±0.00 N/A N/A N/A N/A 9.327±0.00 3.407±0.00 N/A
ENST00000361221 N/A 0.666±0.00 0.493±0.00 0.529±0.00 0.577±0.00 N/A N/A N/A 1.561±0.00 N/A 3.999±0.00 N/A N/A
ENST00000375408 1.466±0.00 N/A 1.621±0.00 3.386±0.00 1.517±0.00 4.042±3.45 N/A N/A 2.131±1.65 18.048±0.00 3.415±2.90 2.170±0.95 1.270±0.00
ENST00000375415 N/A 2.905±0.00 0.682±0.00 0.727±0.00 N/A N/A 6.773±0.00 0.809±0.00 1.736±0.00 3.754±0.00 1.810±0.59 1.174±0.00 N/A
ENST00000469726 N/A 1.121±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000495593 N/A N/A N/A N/A 1.589±0.00 N/A N/A N/A N/A N/A N/A N/A 1.221±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000236 CIL_000236_0002 CGP 1:17406760-17697874

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074244 arhgef10lb Rho guanine nucleotide exchange factor (GEF) 10-like b protein_coding Danio_rerio
ENSDARG00000088630 ARHGEF10L (2 of 2) Rho guanine nucleotide exchange factor (GEF) 10-like protein_coding Danio_rerio
ENSMUSG00000040964 Arhgef10l Rho guanine nucleotide exchange factor (GEF) 10-like protein_coding Mus_musculus

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