C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoprotein membrane anchor with glycosphingolipid microdomains 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000076641 PAG1 9606 - 8:80967810-81112068 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000220597 PAG1-001 80967810-81112068 protein_coding
  ENST00000519326 PAG1-005 81029791-81070176 processed_transcript
  ENST00000522811 PAG1-003 80985228-80987534 retained_intron
  ENST00000523463 PAG1-004 80970291-80975780 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000220597
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000220597 1.559±0.00 2.324±0.00 0.180±0.00 1.680±0.51 0.893±0.19 1.526±0.54 1.143±0.30 1.317±0.18 1.137±0.44 3.643±0.00 0.261±0.05 1.703±0.65 2.723±0.27 0.445±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000088 CIL_000088_0002 CGP 8:80628451-81112068
CIL_00037R CIL_00037R_0001 CGP 8:80967810-81284777

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005070 NAS SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0009967 NAS positive regulation of signal transduction
GO:0016021 IEA integral component of membrane
GO:0035556 IDA intracellular signal transduction
GO:0042169 IDA SH2 domain binding
GO:0045121 IDA membrane raft
GO:0050852 TAS T cell receptor signaling pathway
GO:0050863 IDA regulation of T cell activation
GO:0050868 IEA negative regulation of T cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055875 pag1 ZDB-PUB-030905-1 protein_coding Danio_rerio
ENSMUSG00000027508 Pag1 phosphoprotein associated with glycosphingolipid microdomains 1 protein_coding Mus_musculus

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