C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoprotein associated with glycosphingolipid microdomains 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027508 Pag1 10090 - 3:9687479-9833679 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000108384 Pag1-003 9691898-9833630 protein_coding
  ENSMUST00000159497 Pag1-002 9827436-9833630 processed_transcript
  ENSMUST00000159825 Pag1-004 9692767-9705002 retained_intron
  ENSMUST00000161949 Pag1-001 9687479-9833679 protein_coding
  ENSMUST00000163022 Pag1-005 9752074-9833363 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000108384ENSMUST00000159497ENSMUST00000161949
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000108384 N/A N/A N/A N/A N/A 0.917±0.12 N/A N/A N/A N/A N/A 0.465±0.00 N/A N/A
ENSMUST00000159497 N/A 3.434±0.68 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000161949 1.615±0.17 4.668±1.28 2.432±0.30 2.087±1.03 4.992±1.94 4.125±0.63 0.589±0.16 1.267±0.24 0.944±0.30 10.690±1.62 0.508±0.25 1.574±0.73 1.463±0.59 0.617±0.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000088 CIL_000088_0003 CGP 3:9427011-9833679
CIL_00037R CIL_00037R_0002 CGP 3:9687479-10016607

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002376 IEA immune system process
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0016021 IEA integral component of membrane
GO:0035556 TAS intracellular signal transduction
GO:0042169 IEA SH2 domain binding
GO:0045121 TAS membrane raft
GO:0050863 TAS regulation of T cell activation
GO:0050868 IDA negative regulation of T cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055875 pag1 ZDB-PUB-030905-1 protein_coding Danio_rerio
ENSG00000076641 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 protein_coding Homo_sapiens

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