C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: A-Raf proto-oncogene, serine/threonine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078061 ARAF 9606 + X:47561100-47571920 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290277 ARAF-201 47561100-47571920 protein_coding
  ENST00000377039 ARAF-005 47561222-47565975 protein_coding
  ENST00000377045 ARAF-001 47561117-47571900 protein_coding
  ENST00000469505 ARAF-002 47569459-47570252 processed_transcript
  ENST00000470206 ARAF-003 47569986-47571908 processed_transcript
  ENST00000489496 ARAF-004 47563052-47565233 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377039ENST00000377045ENST00000470206
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377039 N/A N/A N/A N/A N/A N/A N/A N/A 0.952±0.00 N/A 0.657±0.00 N/A N/A
ENST00000377045 22.767±0.00 23.759±0.00 2.851±0.00 14.334±13.32 9.298±8.54 11.173±10.31 31.708±0.00 12.334±10.15 12.838±11.54 21.772±20.71 22.329±17.56 28.882±11.55 11.583±7.55
ENST00000470206 N/A N/A N/A N/A N/A N/A 6.952±0.00 N/A N/A 17.545±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005GC CIL_0005GC_0001 CGP X:47561100-47619853

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005057 IEA receptor signaling protein activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0005739 IEA mitochondrion
GO:0006464 TAS cellular protein modification process
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0032006 IMP regulation of TOR signaling
GO:0032434 IMP regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0035556 IEA intracellular signal transduction
GO:0043066 IDA negative regulation of apoptotic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054533 araf v-raf murine sarcoma 3611 viral oncogene homolog protein_coding Danio_rerio
ENSMUSG00000001127 Araf v-raf murine sarcoma 3611 viral oncogene homolog protein_coding Mus_musculus

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