C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-raf murine sarcoma 3611 viral oncogene homolog
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001127 Araf 10090 + X:20797814-20860519 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001155 Araf-001 20848543-20860519 protein_coding
  ENSMUST00000120356 Araf-004 20848578-20852889 protein_coding
  ENSMUST00000122312 Araf-005 20848566-20852904 protein_coding
  ENSMUST00000122850 Araf-007 20848589-20853450 protein_coding
  ENSMUST00000123219 Araf-010 20851130-20852214 retained_intron
  ENSMUST00000128250 Araf-009 20857723-20860208 protein_coding
  ENSMUST00000136451 Araf-006 20797814-20860497 nonsense_mediated_decay
  ENSMUST00000148032 Araf-002 20848575-20854560 processed_transcript
  ENSMUST00000150190 Araf-008 20848582-20851717 retained_intron
  ENSMUST00000152955 Araf-003 20848564-20855510 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001155ENSMUST00000120356ENSMUST00000122312ENSMUST00000122850ENSMUST00000123219ENSMUST00000136451ENSMUST00000152955
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001155 30.868±6.31 92.268±3.59 25.808±0.47 22.575±0.00 41.745±8.61 57.464±7.14 15.664±3.38 47.954±8.08 32.902±13.33 35.954±5.33 8.351±0.74 53.616±12.52 11.666±6.10 8.410±0.67
ENSMUST00000120356 N/A N/A 24.913±0.00 45.724±5.82 N/A N/A 12.345±0.00 N/A N/A N/A 24.820±3.00 N/A 6.347±2.98 0.473±0.00
ENSMUST00000122312 12.752±2.92 N/A 13.860±0.00 22.751±5.82 20.262±0.00 N/A 7.721±0.73 8.643±0.00 7.344±0.93 20.118±2.61 4.509±0.49 17.622±8.17 5.483±2.65 1.759±0.87
ENSMUST00000122850 27.070±0.00 N/A N/A N/A 39.106±0.00 N/A 24.253±3.45 N/A N/A N/A 15.738±0.00 N/A N/A N/A
ENSMUST00000123219 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.326±0.00
ENSMUST00000136451 11.672±1.45 N/A N/A N/A 11.276±1.68 14.218±0.32 N/A N/A N/A 8.994±0.00 N/A 11.336±1.33 4.014±0.07 N/A
ENSMUST00000152955 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.350±0.00 4.153±1.96 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005GC CIL_0005GC_0002 CGP X:20797814-20921004

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005057 IEA receptor signaling protein activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0006468 IEA protein phosphorylation
GO:0032006 ISS regulation of TOR signaling
GO:0032434 ISS regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 IEA intracellular signal transduction
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054533 araf v-raf murine sarcoma 3611 viral oncogene homolog protein_coding Danio_rerio
ENSG00000078061 ARAF A-Raf proto-oncogene, serine/threonine kinase protein_coding Homo_sapiens

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