C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: A-Raf proto-oncogene, serine/threonine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000377045 ARAF-001 ENSG00000078061 9606 + X:47561117-47571900 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377045
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377045 22.767±0.00 23.759±0.00 2.851±0.00 14.334±13.32 9.298±8.54 11.173±10.31 31.708±0.00 12.334±10.15 12.838±11.54 21.772±20.71 22.329±17.56 28.882±11.55 11.583±7.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005GC CIL_0005GC_0001 CGP X:47561100-47619853

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005057 IEA receptor signaling protein activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0006464 TAS cellular protein modification process
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0032006 IMP regulation of TOR signaling
GO:0032434 IMP regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0035556 IEA intracellular signal transduction
GO:0043066 IDA negative regulation of apoptotic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001155 Araf-001 protein_coding Mus_musculus 0 2542
ENSMUST00000152955 Araf-003 retained_intron Mus_musculus 0 1443
ENSMUST00000148032 Araf-002 processed_transcript Mus_musculus 0 1423
ENSMUST00000136451 Araf-006 nonsense_mediated_decay Mus_musculus 0 1386
ENSMUST00000122850 Araf-007 protein_coding Mus_musculus 0 942
ENSMUST00000120356 Araf-004 protein_coding Mus_musculus 0 835
ENSMUST00000122312 Araf-005 protein_coding Mus_musculus 0 798
ENSMUST00000128250 Araf-009 protein_coding Mus_musculus 0 771
ENSMUST00000123219 Araf-010 retained_intron Mus_musculus 0 496
ENSMUST00000150190 Araf-008 retained_intron Mus_musculus 6e-19 100

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