C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: core-binding factor, runt domain, alpha subunit 2; translocated to, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078699 CBFA2T2 9606 + 20:33490075-33650036 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342704 CBFA2T2-009 33490087-33645541 protein_coding
  ENST00000344201 CBFA2T2-005 33562334-33623954 protein_coding
  ENST00000346541 CBFA2T2-201 33562365-33650031 protein_coding
  ENST00000359606 CBFA2T2-007 33600336-33650036 protein_coding
  ENST00000375279 CBFA2T2-003 33490117-33650036 protein_coding
  ENST00000397800 CBFA2T2-202 33562365-33650031 protein_coding
  ENST00000471007 CBFA2T2-002 33490075-33618546 processed_transcript
  ENST00000491618 CBFA2T2-006 33619565-33636662 processed_transcript
  ENST00000492345 CBFA2T2-004 33562380-33650036 protein_coding
  ENST00000543126 CBFA2T2-203 33638739-33646690 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342704ENST00000344201ENST00000346541ENST00000359606ENST00000375279ENST00000397800ENST00000491618ENST00000492345
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342704 N/A N/A N/A N/A 2.474±0.00 1.295±0.00 N/A 0.458±0.00 1.424±0.00 1.675±0.94 0.864±0.10 2.353±0.77 N/A 4.671±2.07
ENST00000344201 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.912±0.00 N/A N/A N/A N/A
ENST00000346541 N/A N/A N/A 1.403±0.00 1.305±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000359606 1.421±0.00 0.789±0.00 0.578±0.00 1.974±0.00 2.033±0.00 N/A 0.998±0.00 0.940±0.58 N/A 1.918±0.00 1.584±0.00 4.826±3.78 1.834±0.55 3.377±0.73
ENST00000375279 N/A N/A N/A N/A N/A N/A N/A N/A 0.766±0.00 N/A 0.458±0.00 N/A 0.254±0.00 N/A
ENST00000397800 N/A 0.475±0.00 N/A 0.843±0.00 0.766±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000491618 N/A N/A 3.382±0.00 4.286±0.00 N/A 4.112±0.00 1.479±0.00 N/A N/A N/A N/A 15.061±8.50 2.767±0.00 22.905±0.00
ENST00000492345 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.891±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PI CIL_0006PI_0001 CGP 20:33407955-33650036
CIL_00051Z CIL_00051Z_0001 CGP 20:33490075-33674463

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0010976 IDA positive regulation of neuron projection development
GO:0010977 ISS negative regulation of neuron projection development
GO:0030855 IEA epithelial cell differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074337 cbfa2t2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 protein_coding Danio_rerio
ENSMUSG00000038533 Cbfa2t2 core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) protein_coding Mus_musculus

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