C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038533 Cbfa2t2 10090 + 2:154436481-154539356 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045270 Cbfa2t2-002 154436495-154539356 protein_coding
  ENSMUST00000099178 Cbfa2t2-003 154436484-154526413 protein_coding
  ENSMUST00000109724 Cbfa2t2-004 154436535-154517824 protein_coding
  ENSMUST00000109725 Cbfa2t2-001 154436481-154539356 protein_coding
  ENSMUST00000135647 Cbfa2t2-006 154515962-154518052 retained_intron
  ENSMUST00000137526 Cbfa2t2-007 154510536-154539356 protein_coding
  ENSMUST00000139506 Cbfa2t2-009 154531039-154534964 retained_intron
  ENSMUST00000154487 Cbfa2t2-008 154523984-154531599 retained_intron
  ENSMUST00000155202 Cbfa2t2-005 154436842-154504777 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045270ENSMUST00000109724ENSMUST00000109725ENSMUST00000137526ENSMUST00000154487
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045270 4.116±1.41 N/A 4.467±0.57 8.391±3.42 1.854±0.67 3.948±0.00 2.779±0.55 3.416±0.84 1.938±0.64 2.670±0.29 1.821±0.22 3.490±0.65 3.450±1.69 2.724±0.93
ENSMUST00000109724 N/A 5.623±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000109725 1.793±0.00 4.001±0.69 0.964±0.00 1.796±0.00 1.623±0.60 3.466±0.70 0.872±0.00 1.062±0.32 0.744±0.36 2.951±1.57 0.458±0.25 5.123±1.21 0.863±0.06 1.527±0.50
ENSMUST00000137526 1.887±0.43 4.816±1.25 1.952±0.00 3.491±0.60 2.839±0.54 2.631±0.92 0.859±0.00 1.046±0.36 0.825±0.19 1.879±0.37 0.562±0.18 6.533±2.70 1.209±0.01 N/A
ENSMUST00000154487 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.994±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PI CIL_0006PI_0002 CGP 2:154376313-154539356
CIL_00051Z CIL_00051Z_0002 CGP 2:154436481-154558890

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0010976 IEA positive regulation of neuron projection development
GO:0010977 ISS negative regulation of neuron projection development
GO:0030855 IMP epithelial cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074337 cbfa2t2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 protein_coding Danio_rerio
ENSG00000078699 CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 protein_coding Homo_sapiens

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