C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tumor protein p73
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000378285 TP73-004 ENSG00000078900 9606 + 1:3690672-3733292 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryENST00000378285
Transcript ID Ovary
ENST00000378285 0.372±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BY CIL_0002BY_0002 CGP 1:3625002-3652761
CIL_0006BL CIL_0006BL_0002 CGP 1:3630767-3736201

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IBA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IBA chromatin
GO:0002039 IBA p53 binding
GO:0003682 IBA chromatin binding
GO:0003684 IBA damaged DNA binding
GO:0003690 IBA double-stranded DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IBA transcription factor complex
GO:0005829 IBA cytosol
GO:0006298 TAS mismatch repair
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0006978 IBA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0008134 IPI transcription factor binding
GO:0008630 TAS intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010165 IBA response to X-ray
GO:0010332 IBA response to gamma radiation
GO:0019901 IPI protein kinase binding
GO:0031571 IBA mitotic G1 DNA damage checkpoint
GO:0034644 IBA cellular response to UV
GO:0042771 IBA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042802 IPI identical protein binding
GO:0043508 IBA negative regulation of JUN kinase activity
GO:0043524 IBA negative regulation of neuron apoptotic process
GO:0044212 IDA:IEA transcription regulatory region DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0051262 IEA protein tetramerization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105643 Trp73-004 protein_coding Mus_musculus 0 1951
ENSMUST00000133533 Trp73-002 protein_coding Mus_musculus 0 1616
ENSMUST00000105644 Trp73-001 protein_coding Mus_musculus 0 1452
ENSMUST00000097763 Trp73-005 nonsense_mediated_decay Mus_musculus 0 1314
ENSMUST00000097762 Trp73-007 protein_coding Mus_musculus 0 1312
ENSMUST00000155642 Trp73-006 protein_coding Mus_musculus 0 828

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