C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor 7 (T-cell specific, HMG-box)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000081059 TCF7 9606 + 5:134114711-134151865 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342854 TCF7-001 134114711-134147997 protein_coding
  ENST00000378560 TCF7-004 134115607-134148229 protein_coding
  ENST00000395023 TCF7-003 134115625-134148229 protein_coding
  ENST00000395029 TCF7-002 134114712-134148210 protein_coding
  ENST00000517478 TCF7-021 134138104-134141350 processed_transcript
  ENST00000517741 TCF7-020 134115659-134142265 nonsense_mediated_decay
  ENST00000517799 TCF7-009 134142216-134146303 protein_coding
  ENST00000517851 TCF7-011 134115563-134142304 protein_coding
  ENST00000517855 TCF7-023 134142185-134146707 protein_coding
  ENST00000518887 TCF7-010 134115201-134142262 protein_coding
  ENST00000518915 TCF7-006 134115625-134146185 protein_coding
  ENST00000519037 TCF7-014 134123618-134142814 protein_coding
  ENST00000519165 TCF7-017 134115911-134139858 retained_intron
  ENST00000519238 TCF7-008 134141464-134147027 retained_intron
  ENST00000519447 TCF7-013 134115641-134142747 nonsense_mediated_decay
  ENST00000520652 TCF7-018 134115956-134142813 nonsense_mediated_decay
  ENST00000520699 TCF7-022 134142792-134151865 protein_coding
  ENST00000520958 TCF7-024 134115610-134146573 protein_coding
  ENST00000521639 TCF7-012 134115563-134142752 protein_coding
  ENST00000521970 TCF7-016 134137865-134139252 retained_intron
  ENST00000522375 TCF7-015 134115607-134142261 protein_coding
  ENST00000522561 TCF7-019 134138601-134143040 retained_intron
  ENST00000522653 TCF7-005 134115352-134147983 retained_intron
  ENST00000524342 TCF7-007 134140535-134148236 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalENST00000395023
Transcript ID Adrenal
ENST00000395023 34.417±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GN CIL_0000GN_0002 CGP 5:134114711-134177038

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003682 IBA chromatin binding
GO:0003700 IBA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IBA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA:IBA regulation of transcription from RNA polymerase II promoter
GO:0006955 TAS immune response
GO:0007420 IBA brain development
GO:0008013 IEA:IDA beta-catenin binding
GO:0016055 IEA Wnt signaling pathway
GO:0021915 IEA neural tube development
GO:0030538 IEA embryonic genitalia morphogenesis
GO:0033153 IEA T cell receptor V(D)J recombination
GO:0042127 IEA regulation of cell proliferation
GO:0043565 IBA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044336 IEA canonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0046632 IEA alpha-beta T cell differentiation
GO:0048557 IEA embryonic digestive tract morphogenesis
GO:0048619 IEA embryonic hindgut morphogenesis
GO:0048699 IBA generation of neurons
GO:0060070 IBA canonical Wnt signaling pathway
GO:0071353 IDA cellular response to interleukin-4

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038672 tcf7 transcription factor 7 (T-cell specific, HMG-box) protein_coding Danio_rerio
ENSMUSG00000000782 Tcf7 transcription factor 7, T cell specific protein_coding Mus_musculus

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