C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor 7, T cell specific
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000782 Tcf7 10090 - 11:52252371-52283014 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086844 Tcf7-001 52252371-52282571 protein_coding
  ENSMUST00000109071 Tcf7-002 52253236-52283014 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086844ENSMUST00000109071
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086844 N/A N/A 1.572±0.57 1.009±0.00 13.883±4.76 0.922±0.24 0.372±0.12 1.461±0.69 0.978±0.59 2.514±0.32 0.506±0.73 6.321±3.69 1.316±0.62 N/A
ENSMUST00000109071 0.347±0.00 8.774±1.60 N/A 0.884±0.08 26.828±14.13 0.874±0.50 0.281±0.20 0.895±0.25 0.679±0.49 4.058±0.16 N/A 5.333±2.17 1.498±1.06 0.595±0.23

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003682 IBA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005667 IBA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0007420 IBA brain development
GO:0008013 IBA beta-catenin binding
GO:0016055 IDA Wnt signaling pathway
GO:0021915 IGI neural tube development
GO:0030538 IGI embryonic genitalia morphogenesis
GO:0033153 IGI T cell receptor V(D)J recombination
GO:0042127 IDA regulation of cell proliferation
GO:0043565 IBA sequence-specific DNA binding
GO:0044212 IBA transcription regulatory region DNA binding
GO:0044336 IDA canonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0046632 IGI alpha-beta T cell differentiation
GO:0048557 IGI embryonic digestive tract morphogenesis
GO:0048619 IGI embryonic hindgut morphogenesis
GO:0048699 IBA generation of neurons
GO:0071353 IEA cellular response to interleukin-4

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038672 tcf7 transcription factor 7 (T-cell specific, HMG-box) protein_coding Danio_rerio
ENSG00000081059 TCF7 transcription factor 7 (T-cell specific, HMG-box) protein_coding Homo_sapiens

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