C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000083642 PDS5B 9606 + 13:32586427-32778019 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000315596 PDS5B-006 32586427-32778019 protein_coding
  ENST00000447833 PDS5B-012 32758169-32770546 protein_coding
  ENST00000450460 PDS5B-007 32586548-32775908 nonsense_mediated_decay
  ENST00000466078 PDS5B-002 32586569-32650617 retained_intron
  ENST00000474274 PDS5B-010 32770190-32771079 retained_intron
  ENST00000481616 PDS5B-004 32700984-32710068 retained_intron
  ENST00000482955 PDS5B-011 32586455-32658349 retained_intron
  ENST00000493653 PDS5B-008 32586551-32652605 retained_intron
  ENST00000498550 PDS5B-009 32586543-32691268 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000315596ENST00000447833ENST00000450460ENST00000474274ENST00000498550
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000315596 2.971±0.00 N/A N/A 5.625±0.61 1.266±0.00 1.951±0.41 1.013±0.43 1.197±0.00 2.015±1.32 1.945±0.81 2.724±0.00 3.009±1.03 1.340±0.34 4.455±1.73
ENST00000447833 N/A N/A N/A N/A N/A 7.568±0.00 N/A 2.377±0.00 2.373±0.00 6.276±0.00 N/A 13.060±0.00 6.523±0.00 11.099±0.00
ENST00000450460 3.073±0.00 2.549±0.00 0.742±0.00 2.906±0.00 1.495±0.00 2.464±0.00 0.952±0.00 1.426±0.41 1.043±0.80 2.287±0.00 N/A 1.835±0.29 1.017±0.36 2.015±0.25
ENST00000474274 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.880±0.00 4.294±0.00 N/A
ENST00000498550 N/A N/A 1.714±0.00 N/A 3.795±0.00 N/A 0.780±0.00 1.107±0.00 3.710±0.00 6.908±0.00 0.387±0.00 5.796±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000UY CIL_0000UY_0001 CGP 13:32586427-33066145

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0000775 TAS chromosome, centromeric region
GO:0000785 IDA chromatin
GO:0003677 IEA DNA binding
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005524 TAS ATP binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005694 TAS chromosome
GO:0005829 TAS cytosol
GO:0007064 IMP mitotic sister chromatid cohesion
GO:0008283 TAS cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0042127 IDA regulation of cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061312 pds5b PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000034021 Pds5b PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) protein_coding Mus_musculus

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