C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: epidermal growth factor receptor pathway substrate 15
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000371733 EPS15-001 ENSG00000085832 9606 - 1:51354263-51519328 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371733
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371733 16.816±0.00 13.115±0.00 2.109±0.00 20.986±0.00 13.085±1.21 8.523±1.53 8.321±2.85 8.297±1.77 8.052±4.36 9.892±2.97 10.518±8.51 6.661±3.11 5.971±1.82 13.998±9.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006W8 CIL_0006W8_0002 CGP 1:51287258-51519328

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005905 TAS coated pit
GO:0006895 IMP Golgi to endosome transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008283 TAS cell proliferation
GO:0015031 IEA protein transport
GO:0016020 IDA membrane
GO:0016050 TAS vesicle organization
GO:0017124 IEA SH3 domain binding
GO:0030122 IEA AP-2 adaptor complex
GO:0030132 IEA clathrin coat of coated pit
GO:0030136 IEA clathrin-coated vesicle
GO:0031593 IDA polyubiquitin binding
GO:0032456 IC endocytic recycling
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0042802 IEA identical protein binding
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0048268 IDA clathrin coat assembly
GO:0060170 IEA ciliary membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102729 Eps15-001 protein_coding Mus_musculus 0 3733
ENSMUST00000176251 Eps15-008 nonsense_mediated_decay Mus_musculus 0 2998
ENSMUST00000175776 Eps15-005 protein_coding Mus_musculus 0 2414
ENSMUST00000030281 Eps15-002 protein_coding Mus_musculus 0 2145
ENSMUST00000132165 Eps15-011 protein_coding Mus_musculus 0 1779
ENSMUST00000126015 Eps15-006 retained_intron Mus_musculus 0 628
ENSMUST00000177089 Eps15-007 protein_coding Mus_musculus 0 366
ENSMUST00000141751 Eps15-004 retained_intron Mus_musculus 0 339
ENSMUST00000177140 Eps15-009 processed_transcript Mus_musculus 3e-25 122

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