C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane emp24 domain trafficking protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000086598 TMED2 9606 + 12:123584531-123598577 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262225 TMED2-001 123584531-123598577 protein_coding
  ENST00000438031 TMED2-003 123584533-123590446 protein_coding
  ENST00000509052 TMED2-004 123585562-123597093 protein_coding
  ENST00000543425 TMED2-006 123584549-123597342 retained_intron
  ENST00000544188 TMED2-005 123584598-123586960 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262225ENST00000438031ENST00000543425ENST00000544188
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262225 N/A N/A 11.652±0.00 24.223±0.00 46.058±0.00 31.330±0.00 4.378±0.00 46.982±0.00 37.191±0.00 31.665±0.00 N/A 57.392±26.84 30.194±26.47 20.928±0.00
ENST00000438031 N/A N/A N/A N/A N/A N/A 7.479±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000543425 42.044±0.00 15.597±0.00 4.807±0.00 27.340±0.00 45.494±0.00 8.648±0.00 N/A N/A N/A N/A 2.640±0.00 38.779±0.00 27.879±0.00 23.701±12.55
ENST00000544188 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 153.189±0.00 144.143±0.00 64.140±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003J9 CIL_0003J9_0001 CGP 12:123470054-123598577
CIL_0003J8 CIL_0003J8_0001 CGP 12:123584531-123620941

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001893 IEA maternal placenta development
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0005793 IDA endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 IDA Golgi apparatus
GO:0006810 IEA transport
GO:0006886 IDA intracellular protein transport
GO:0006888 TAS ER to Golgi vesicle-mediated transport
GO:0007030 IMP Golgi organization
GO:0016021 IEA:ISS integral component of membrane
GO:0030137 ISS COPI-coated vesicle
GO:0034260 IDA negative regulation of GTPase activity
GO:0035459 TAS cargo loading into vesicle
GO:0042589 ISS zymogen granule membrane
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0048205 TAS COPI coating of Golgi vesicle
GO:0048208 TAS COPII vesicle coating
GO:0048598 IEA embryonic morphogenesis
GO:0072661 IDA protein targeting to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026908 tmed2 transmembrane emp24 domain trafficking protein 2 protein_coding Danio_rerio
ENSMUSG00000029390 Tmed2 transmembrane emp24 domain trafficking protein 2 protein_coding Mus_musculus

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