C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adducin 1 (alpha)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000087274 ADD1 9606 + 4:2843857-2930076 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264758 ADD1-201 2843857-2930073 protein_coding
  ENST00000355842 ADD1-002 2844150-2930062 protein_coding
  ENST00000374281 ADD1-026 2853134-2868095 processed_transcript
  ENST00000398123 ADD1-003 2875896-2928523 protein_coding
  ENST00000398125 ADD1-202 2843857-2930073 protein_coding
  ENST00000398129 ADD1-001 2875896-2930076 protein_coding
  ENST00000446856 ADD1-203 2843922-2930073 protein_coding
  ENST00000503062 ADD1-016 2926309-2928291 retained_intron
  ENST00000503169 ADD1-006 2867875-2905721 retained_intron
  ENST00000503455 ADD1-013 2843987-2929327 protein_coding
  ENST00000506157 ADD1-007 2887504-2902914 retained_intron
  ENST00000508277 ADD1-009 2843982-2894733 protein_coding
  ENST00000508684 ADD1-008 2843857-2900313 retained_intron
  ENST00000509039 ADD1-005 2843979-2899777 retained_intron
  ENST00000510101 ADD1-010 2843872-2894684 nonsense_mediated_decay
  ENST00000511797 ADD1-011 2843945-2884569 protein_coding
  ENST00000513328 ADD1-014 2843973-2929307 protein_coding
  ENST00000513762 ADD1-012 2907377-2930076 retained_intron
  ENST00000514940 ADD1-015 2898431-2928431 protein_coding
  ENST00000534870 ADD1-017 2881600-2894682 retained_intron
  ENST00000536078 ADD1-019 2904664-2907813 retained_intron
  ENST00000536424 ADD1-022 2907830-2928560 protein_coding
  ENST00000538860 ADD1-024 2928603-2930062 processed_transcript
  ENST00000539108 ADD1-025 2843953-2854950 processed_transcript
  ENST00000539149 ADD1-021 2914705-2926137 retained_intron
  ENST00000540541 ADD1-018 2843989-2876405 retained_intron
  ENST00000541051 ADD1-020 2907204-2926100 retained_intron
  ENST00000541843 ADD1-023 2914942-2928346 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264758ENST00000398123ENST00000398125ENST00000398129ENST00000446856ENST00000509039ENST00000510101ENST00000514940
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264758 N/A 17.044±0.00 N/A 16.351±0.00 28.522±0.00 8.444±0.00 12.562±0.00 N/A N/A 17.759±0.00 7.668±0.00 12.873±0.00 10.454±0.00
ENST00000398123 N/A N/A 11.697±0.00 N/A N/A 3.271±0.00 N/A 10.267±0.00 N/A 5.123±0.00 N/A N/A N/A
ENST00000398125 N/A N/A 21.557±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000398129 N/A 36.493±0.00 19.927±0.00 15.812±2.20 11.926±2.71 9.843±4.36 18.032±12.60 17.344±2.87 19.213±9.91 22.304±19.55 42.511±31.10 54.396±0.82 19.399±9.01
ENST00000446856 17.170±0.00 19.637±0.00 39.028±0.00 24.215±0.00 35.087±0.00 12.893±0.00 12.811±0.00 6.406±0.00 28.634±0.00 19.710±0.00 33.988±0.00 N/A 30.254±0.00
ENST00000509039 N/A N/A N/A N/A N/A N/A N/A N/A 16.987±0.00 N/A 9.270±0.00 N/A N/A
ENST00000510101 N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.361±0.00 N/A N/A N/A
ENST00000514940 N/A N/A 78.696±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 30.304±2.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074C CIL_00074C_0001 CGP 4:2793023-2930076
CIL_00056E CIL_00056E_0001 CGP 4:2843857-2934859

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IEA cell morphogenesis
GO:0001701 IEA in utero embryonic development
GO:0003779 TAS actin binding
GO:0005198 IEA structural molecule activity
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006884 IEA cell volume homeostasis
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0008134 IPI transcription factor binding
GO:0008290 IDA F-actin capping protein complex
GO:0014069 IEA postsynaptic density
GO:0016020 IEA membrane
GO:0020027 IEA hemoglobin metabolic process
GO:0030036 IC actin cytoskeleton organization
GO:0030218 IEA erythrocyte differentiation
GO:0030425 IEA dendrite
GO:0030507 IDA spectrin binding
GO:0030837 IEA negative regulation of actin filament polymerization
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0032092 IDA positive regulation of protein binding
GO:0035264 IEA multicellular organism growth
GO:0042608 IEA T cell receptor binding
GO:0042803 IPI protein homodimerization activity
GO:0043197 IEA dendritic spine
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045111 IDA intermediate filament cytoskeleton
GO:0045202 IEA synapse
GO:0045766 IEA positive regulation of angiogenesis
GO:0045807 IEA positive regulation of endocytosis
GO:0046982 IPI protein heterodimerization activity
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048873 IEA homeostasis of number of cells within a tissue
GO:0051015 IDA actin filament binding
GO:0051016 IDA barbed-end actin filament capping
GO:0051017 IDA actin filament bundle assembly
GO:0071300 IEA cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022682 add1 adducin 1 (alpha) protein_coding Danio_rerio
ENSMUSG00000029106 Add1 adducin 1 (alpha) protein_coding Mus_musculus

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