C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adducin 1 (alpha)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029106 Add1 10090 + 5:34573664-34632308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001108 Add1-002 34573863-34632305 protein_coding
  ENSMUST00000052836 Add1-004 34601342-34630816 protein_coding
  ENSMUST00000114335 Add1-003 34574042-34632294 protein_coding
  ENSMUST00000114338 Add1-001 34573664-34632308 protein_coding
  ENSMUST00000114340 Add1-005 34573873-34632308 protein_coding
  ENSMUST00000135321 Add1-006 34614247-34625319 protein_coding
  ENSMUST00000137262 Add1-011 34619849-34630741 retained_intron
  ENSMUST00000139044 Add1-012 34619971-34628743 retained_intron
  ENSMUST00000144226 Add1-010 34616626-34620451 retained_intron
  ENSMUST00000145986 Add1-008 34573804-34601625 processed_transcript
  ENSMUST00000146295 Add1-009 34573769-34605893 protein_coding
  ENSMUST00000147574 Add1-007 34573765-34605893 protein_coding
  ENSMUST00000152805 Add1-013 34619354-34632308 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001108ENSMUST00000052836ENSMUST00000114335ENSMUST00000114338ENSMUST00000114340ENSMUST00000139044ENSMUST00000144226ENSMUST00000152805
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001108 N/A N/A N/A 23.083±2.05 N/A N/A N/A N/A N/A N/A 1.955±0.03 N/A N/A N/A
ENSMUST00000052836 N/A N/A N/A 78.323±0.00 N/A N/A N/A N/A N/A N/A N/A 19.143±0.00 N/A 2.732±0.00
ENSMUST00000114335 N/A N/A N/A N/A N/A N/A 3.553±0.01 N/A N/A N/A 2.303±0.51 N/A N/A N/A
ENSMUST00000114338 8.401±0.00 7.951±1.33 N/A 25.782±2.56 11.614±0.54 21.409±3.04 8.853±3.90 6.122±0.85 23.424±16.79 14.950±3.94 N/A 14.417±3.97 7.403±0.09 2.912±0.47
ENSMUST00000114340 39.106±9.76 15.717±1.99 56.959±4.26 18.838±8.29 26.190±3.55 27.787±2.40 14.917±2.60 23.580±1.82 11.560±8.81 41.542±4.88 10.970±1.47 34.892±15.43 34.350±9.16 6.990±2.75
ENSMUST00000139044 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 73.402±0.00 53.608±0.00 8.993±0.00
ENSMUST00000144226 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 69.922±0.00 53.551±4.80 9.299±0.00
ENSMUST00000152805 19.333±2.66 35.097±1.64 21.379±0.00 23.454±7.77 35.705±10.29 53.557±8.04 9.677±2.83 17.322±7.19 26.600±10.69 29.022±5.21 N/A 49.610±8.20 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074C CIL_00074C_0002 CGP 5:34525838-34632308
CIL_00056E CIL_00056E_0002 CGP 5:34573664-34637212

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IMP cell morphogenesis
GO:0001701 IMP in utero embryonic development
GO:0005198 IDA structural molecule activity
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005634 IEA nucleus
GO:0005856 IDA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005925 IEA focal adhesion
GO:0006884 IMP cell volume homeostasis
GO:0008134 IEA transcription factor binding
GO:0008290 IEA F-actin capping protein complex
GO:0014069 IEA postsynaptic density
GO:0016020 IDA membrane
GO:0020027 IMP hemoglobin metabolic process
GO:0030218 IMP erythrocyte differentiation
GO:0030425 IEA dendrite
GO:0030507 IEA spectrin binding
GO:0030837 IEA negative regulation of actin filament polymerization
GO:0032092 IEA positive regulation of protein binding
GO:0035264 IMP multicellular organism growth
GO:0042608 IEA T cell receptor binding
GO:0042803 IEA protein homodimerization activity
GO:0043197 IEA dendritic spine
GO:0044822 IEA poly(A) RNA binding
GO:0045111 IEA intermediate filament cytoskeleton
GO:0045202 IEA synapse
GO:0045766 IEA positive regulation of angiogenesis
GO:0045807 IEA positive regulation of endocytosis
GO:0046982 IEA protein heterodimerization activity
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048873 IMP homeostasis of number of cells within a tissue
GO:0051015 IEA actin filament binding
GO:0051016 IEA barbed-end actin filament capping
GO:0051017 IEA actin filament bundle assembly
GO:0071300 IEA cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022682 add1 adducin 1 (alpha) protein_coding Danio_rerio
ENSG00000087274 ADD1 adducin 1 (alpha) protein_coding Homo_sapiens

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