C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adducin 1 (alpha)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000398129 ADD1-001 ENSG00000087274 9606 + 4:2875896-2930076 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000398129
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000398129 36.493±0.00 19.927±0.00 15.812±2.20 11.926±2.71 9.843±4.36 18.032±12.60 17.344±2.87 19.213±9.91 22.304±19.55 42.511±31.10 54.396±0.82 19.399±9.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074C CIL_00074C_0001 CGP 4:2793023-2930076
CIL_00056E CIL_00056E_0001 CGP 4:2843857-2934859

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003779 TAS actin binding
GO:0005516 IEA calmodulin binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0008134 IPI transcription factor binding
GO:0008290 IDA F-actin capping protein complex
GO:0030036 IC actin cytoskeleton organization
GO:0030507 IDA spectrin binding
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0032092 IDA positive regulation of protein binding
GO:0042803 IPI protein homodimerization activity
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045111 IDA intermediate filament cytoskeleton
GO:0046982 IPI protein heterodimerization activity
GO:0051015 IDA actin filament binding
GO:0051016 IDA barbed-end actin filament capping
GO:0051017 IDA actin filament bundle assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000114340 Add1-005 protein_coding Mus_musculus 0 2726
ENSMUST00000114338 Add1-001 protein_coding Mus_musculus 0 2410
ENSMUST00000114335 Add1-003 protein_coding Mus_musculus 0 2134
ENSMUST00000001108 Add1-002 protein_coding Mus_musculus 0 1827
ENSMUST00000052836 Add1-004 protein_coding Mus_musculus 0 1816
ENSMUST00000152805 Add1-013 protein_coding Mus_musculus 0 577
ENSMUST00000144226 Add1-010 retained_intron Mus_musculus 0 556
ENSMUST00000146295 Add1-009 protein_coding Mus_musculus 0 523
ENSMUST00000147574 Add1-007 protein_coding Mus_musculus 0 523
ENSMUST00000135321 Add1-006 protein_coding Mus_musculus 0 505
ENSMUST00000145986 Add1-008 processed_transcript Mus_musculus 0 261

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