C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000087510 TFAP2C 9606 + 20:56629302-56639283 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000201031 TFAP2C-001 56629302-56639283 protein_coding
  ENST00000416606 TFAP2C-002 56630234-56631547 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000201031
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000201031 0.310±0.00 0.062±0.00 0.030±0.00 5.453±4.44 0.678±0.00 0.096±0.00 0.498±0.40 0.182±0.18 0.840±0.68 1.004±0.67 13.245±3.45 1.122±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099D CIL_00099D_0001 VISTA 20:56155251-56756351
CIL_0003D9 CIL_0003D9_0001 CGP 20:56533246-56639283
CIL_000339 CIL_000339_0001 CGP 20:56629302-57266629

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001047 IDA core promoter binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001829 IEA trophectodermal cell differentiation
GO:0001942 IEA hair follicle development
GO:0003334 IEA keratinocyte development
GO:0003677 IDA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007267 TAS cell-cell signaling
GO:0008584 IEP male gonad development
GO:0019827 IEA stem cell maintenance
GO:0021877 IEA forebrain neuron fate commitment
GO:0021987 IEA cerebral cortex development
GO:0030154 IEA cell differentiation
GO:0030718 IEA germ-line stem cell maintenance
GO:0035019 IEA somatic stem cell maintenance
GO:0040029 IMP regulation of gene expression, epigenetic
GO:0043588 IEA skin development
GO:0045682 IEA regulation of epidermis development
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IDA protein dimerization activity
GO:0048733 IEA sebaceous gland development
GO:0060598 IEA dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
GO:0060750 IEA epithelial cell proliferation involved in mammary gland duct elongation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040606 tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) protein_coding Danio_rerio
ENSMUSG00000028640 Tfap2c transcription factor AP-2, gamma protein_coding Mus_musculus

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