C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor AP-2, gamma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028640 Tfap2c 10090 + 2:172549593-172558622 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030391 Tfap2c-001 172549593-172558622 protein_coding
  ENSMUST00000099058 Tfap2c-004 172550782-172558619 protein_coding
  ENSMUST00000122982 Tfap2c-003 172550764-172557826 processed_transcript
  ENSMUST00000128406 Tfap2c-002 172550653-172558607 processed_transcript
  ENSMUST00000142633 Tfap2c-005 172552116-172553518 processed_transcript
  ENSMUST00000170744 Tfap2c-201 172550991-172558619 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030391ENSMUST00000099058ENSMUST00000122982ENSMUST00000128406ENSMUST00000170744
Transcript ID Adipose Bladder Brain Breast Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030391 0.374±0.08 1.807±0.22 3.057±1.87 2.760±0.99 N/A 0.024±0.00 0.207±0.03 0.031±0.00 0.417±0.27 30.486±11.80 0.069±0.03
ENSMUST00000099058 0.140±0.00 0.766±0.00 0.501±0.00 0.903±0.15 N/A N/A 0.067±0.03 N/A 0.459±0.06 6.938±1.09 0.033±0.00
ENSMUST00000122982 N/A N/A N/A 0.511±0.00 0.024±0.01 N/A 0.061±0.04 N/A 0.030±0.00 21.320±0.00 0.039±0.00
ENSMUST00000128406 N/A N/A N/A N/A N/A 0.008±0.00 N/A 0.014±0.01 0.135±0.07 N/A N/A
ENSMUST00000170744 N/A N/A 0.026±0.00 0.937±0.00 N/A 0.012±0.00 N/A 0.022±0.01 0.427±0.20 N/A 0.048±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099D CIL_00099D_0002 VISTA 2:172130534-172731364
CIL_0003D9 CIL_0003D9_0002 CGP 2:172472520-172558622
CIL_000339 CIL_000339_0002 CGP 2:172549593-172940321

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001047 IEA core promoter binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001829 IMP trophectodermal cell differentiation
GO:0001942 IGI hair follicle development
GO:0003334 IGI keratinocyte development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0008584 IEA male gonad development
GO:0019827 IDA stem cell maintenance
GO:0021877 IMP forebrain neuron fate commitment
GO:0021987 IMP cerebral cortex development
GO:0030154 IMP cell differentiation
GO:0030718 IMP germ-line stem cell maintenance
GO:0035019 IMP somatic stem cell maintenance
GO:0040029 IEA regulation of gene expression, epigenetic
GO:0043588 IGI skin development
GO:0045682 IMP regulation of epidermis development
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0048733 IGI sebaceous gland development
GO:0060598 IMP dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
GO:0060750 IMP epithelial cell proliferation involved in mammary gland duct elongation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040606 tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) protein_coding Danio_rerio
ENSG00000087510 TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) protein_coding Homo_sapiens

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