C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ER degradation enhancer, mannosidase alpha-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000088298 EDEM2 9606 - 20:35115357-35147364 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374491 EDEM2-002 35115364-35147319 protein_coding
  ENST00000374492 EDEM2-001 35115357-35147364 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374491ENST00000374492
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374491 N/A N/A 0.770±0.00 N/A 1.052±0.00 0.638±0.34 9.482±0.00 3.715±2.42 2.819±0.00 0.969±0.12 3.755±1.86 7.316±0.00 1.759±0.00
ENST00000374492 7.656±0.00 12.850±0.00 1.890±1.07 4.702±3.28 2.140±1.83 1.744±1.53 6.765±2.54 13.037±0.00 4.831±2.27 2.637±0.00 5.075±3.57 29.526±3.48 4.614±1.67

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006AB CIL_0006AB_0001 CGP 20:35002404-35147364
CIL_0008EI CIL_0008EI_0001 VISTA 20:35018152-35620688

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004571 IEA mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 IEA calcium ion binding
GO:0005576 IEA extracellular region
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006457 TAS protein folding
GO:0006986 IEA response to unfolded protein
GO:0016020 IEA membrane
GO:0018279 TAS protein N-linked glycosylation via asparagine
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028448 edem2 ER degradation enhancer, mannosidase alpha-like 2 protein_coding Danio_rerio
ENSMUSG00000038312 Edem2 ER degradation enhancer, mannosidase alpha-like 2 protein_coding Mus_musculus

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