C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cardiolipin synthase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000088766 CRLS1 9606 + 20:6006090-6040053 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000378863 CRLS1-001 6006090-6040053 protein_coding
  ENST00000378868 CRLS1-005 6007252-6037393 protein_coding
  ENST00000452938 CRLS1-201 6006093-6040043 protein_coding
  ENST00000464921 CRLS1-004 6028271-6034555 processed_transcript
  ENST00000478846 CRLS1-003 6031163-6037391 processed_transcript
  ENST00000489345 CRLS1-002 6009779-6034523 processed_transcript
  ENST00000609154 CRLS1-006 6007256-6016055 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378863ENST00000378868ENST00000452938ENST00000478846ENST00000489345
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378863 3.563±0.00 1.331±0.00 0.451±0.00 1.228±0.09 2.544±0.83 1.829±0.16 4.958±2.67 6.312±1.11 7.568±0.00 N/A 1.947±1.13 4.268±1.59 1.978±0.48 3.271±1.28
ENST00000378868 11.153±0.00 3.641±0.00 2.724±0.00 2.891±1.03 8.262±5.07 8.990±0.00 17.151±11.23 12.438±0.66 16.087±11.72 14.442±0.00 8.121±3.61 10.572±5.03 7.643±2.45 12.174±2.51
ENST00000452938 N/A N/A N/A 0.686±0.00 N/A N/A N/A N/A N/A 3.819±0.00 N/A N/A N/A N/A
ENST00000478846 7.604±0.00 3.917±0.00 N/A N/A N/A 3.527±0.00 N/A N/A N/A N/A N/A 8.975±0.00 N/A N/A
ENST00000489345 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.298±0.00 4.802±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007A0 CIL_0007A0_0002 CGP 20:5950652-6040053
CIL_0002H5 CIL_0002H5_0001 CGP 20:6006090-6054049

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005739 IEA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006644 TAS phospholipid metabolic process
GO:0008444 IEA CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
GO:0008654 IEA phospholipid biosynthetic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016780 IEA phosphotransferase activity, for other substituted phosphate groups
GO:0032049 TAS cardiolipin biosynthetic process
GO:0036148 TAS phosphatidylglycerol acyl-chain remodeling
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038000 crls1 cardiolipin synthase 1 protein_coding Danio_rerio
ENSMUSG00000027357 Crls1 cardiolipin synthase 1 protein_coding Mus_musculus

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