C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FUS RNA binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000089280 FUS 9606 + 16:31180110-31194871 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254108 FUS-001 31180110-31194871 protein_coding
  ENST00000380244 FUS-008 31180139-31191602 protein_coding
  ENST00000474990 FUS-004 31185499-31191102 processed_transcript
  ENST00000483853 FUS-007 31190373-31191558 retained_intron
  ENST00000487045 FUS-002 31180139-31183350 retained_intron
  ENST00000487509 FUS-006 31180150-31191602 retained_intron
  ENST00000487974 FUS-003 31183550-31184398 retained_intron
  ENST00000564766 FUS-022 31188467-31189695 retained_intron
  ENST00000566605 FUS-010 31180138-31191602 nonsense_mediated_decay
  ENST00000568685 FUS-016 31180151-31191575 protein_coding
  ENST00000568901 FUS-019 31188152-31190120 retained_intron
  ENST00000569760 FUS-020 31190216-31191605 retained_intron
  ENST00000570090 FUS-018 31185080-31187245 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254108ENST00000380244ENST00000474990ENST00000487509ENST00000566605ENST00000568685ENST00000568901ENST00000569760
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254108 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.751±0.00 N/A N/A N/A
ENST00000380244 28.320±0.00 57.799±0.00 N/A 45.999±0.00 21.945±0.00 15.275±0.00 26.663±0.00 35.378±0.00 7.087±0.00 13.545±0.00 16.012±0.00 100.859±24.86 83.972±21.99 62.960±26.88
ENST00000474990 108.157±0.00 288.326±0.00 N/A 131.635±0.00 74.681±0.00 33.956±0.00 N/A 74.316±0.00 15.461±0.00 17.930±0.00 14.983±0.00 177.989±57.62 41.472±0.00 129.686±0.00
ENST00000487509 N/A 18.555±0.00 2.998±0.00 5.597±0.00 6.776±0.51 4.411±2.03 2.876±2.72 5.054±4.00 1.391±0.01 4.122±1.29 N/A 11.870±6.32 N/A 13.866±8.85
ENST00000566605 N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.582±0.00 N/A N/A 33.685±6.25 43.182±0.00
ENST00000568685 32.082±0.00 74.818±0.00 N/A 29.899±0.00 N/A N/A N/A N/A 10.330±0.00 13.455±0.00 11.493±0.00 51.459±18.52 N/A 28.920±0.00
ENST00000568901 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 83.276±0.00 N/A 102.970±0.00
ENST00000569760 N/A N/A N/A N/A N/A N/A N/A N/A 24.280±0.00 30.691±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044X CIL_00044X_0002 CGP 16:31138925-31194871

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003723 TAS RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0008219 IEA cell death
GO:0008270 IEA zinc ion binding
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0042802 IPI identical protein binding
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037968 fus fusion (involved in t(12;16) in malignant liposarcoma) protein_coding Danio_rerio
ENSMUSG00000030795 Fus fused in sarcoma protein_coding Mus_musculus

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