C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine palmitoyltransferase, long chain base subunit 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000090054 SPTLC1 9606 - 9:92031999-92115384 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262554 SPTLC1-001 92031999-92115376 protein_coding
  ENST00000337841 SPTLC1-002 92079061-92115383 protein_coding
  ENST00000461132 SPTLC1-005 92108160-92115338 processed_transcript
  ENST00000469778 SPTLC1-008 92032354-92038458 processed_transcript
  ENST00000477888 SPTLC1-007 92079853-92108768 processed_transcript
  ENST00000482632 SPTLC1-006 92059179-92115384 processed_transcript
  ENST00000488921 SPTLC1-004 92107801-92115382 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262554ENST00000469778
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262554 5.313±0.00 5.364±0.00 3.179±0.25 1.860±0.00 1.684±0.00 1.852±0.00 2.973±0.00 6.539±0.00 2.347±0.00 20.758±12.48 25.431±0.00 20.156±0.00
ENST00000469778 N/A N/A N/A N/A N/A N/A N/A N/A N/A 55.214±0.00 29.601±0.00 34.674±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002JG CIL_0002JG_0001 CGP 9:91563091-92115384

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004758 IDA serine C-palmitoyltransferase activity
GO:0005515 IPI protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006665 TAS sphingolipid metabolic process
GO:0006686 IEA sphingomyelin biosynthetic process
GO:0009058 IEA biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0017059 IDA serine C-palmitoyltransferase complex
GO:0030148 TAS sphingolipid biosynthetic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0035339 IDA SPOTS complex
GO:0044281 TAS small molecule metabolic process
GO:0046511 IEA sphinganine biosynthetic process
GO:0046512 IEA sphingosine biosynthetic process
GO:0046513 IEA ceramide biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042995 sptlc1 serine palmitoyltransferase, long chain base subunit 1 protein_coding Danio_rerio
ENSMUSG00000021468 Sptlc1 serine palmitoyltransferase, long chain base subunit 1 protein_coding Mus_musculus

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