C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: AlkB family member 5, RNA demethylase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000091542 ALKBH5 9606 + 17:18183078-18209954 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000399138 ALKBH5-001 18184239-18209954 protein_coding
  ENST00000490106 ALKBH5-002 18206561-18209954 retained_intron
  ENST00000541285 ALKBH5-003 18183078-18209398 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000399138ENST00000490106ENST00000541285
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000399138 42.890±0.00 35.360±0.00 5.818±0.00 31.922±15.88 23.678±13.85 28.362±16.27 36.866±24.61 28.452±9.31 24.247±3.01 26.344±15.65 83.953±37.42 32.041±18.91 22.930±1.51 88.820±18.34
ENST00000490106 N/A N/A N/A 3.939±0.00 2.058±0.00 N/A 2.799±0.00 N/A 4.098±0.00 2.673±0.00 N/A 4.481±0.79 N/A N/A
ENST00000541285 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.430±0.00 16.731±0.00 41.198±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00058Q CIL_00058Q_0002 CGP 17:18108706-18209954
CIL_0000E2 CIL_0000E2_0001 CGP 17:18183078-18244875

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0005634 IDA nucleus
GO:0006397 IMP mRNA processing
GO:0006406 IMP mRNA export from nucleus
GO:0007283 ISS spermatogenesis
GO:0016607 IDA nuclear speck
GO:0016706 IDA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0030154 IEA cell differentiation
GO:0035515 IDA oxidative RNA demethylase activity
GO:0035553 IDA oxidative single-stranded RNA demethylation
GO:0044822 IDA poly(A) RNA binding
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063003 alkbh5 alkB, alkylation repair homolog 5 (E. coli) protein_coding Danio_rerio
ENSMUSG00000042650 Alkbh5 alkB, alkylation repair homolog 5 (E. coli) protein_coding Mus_musculus

Loading