C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calpain 3, (p94)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000092529 CAPN3 9606 + 15:42359500-42412318 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318023 CAPN3-201 42359500-42412317 protein_coding
  ENST00000337571 CAPN3-006 42404779-42412315 protein_coding
  ENST00000349748 CAPN3-005 42359585-42412317 protein_coding
  ENST00000356316 CAPN3-202 42404779-42412317 protein_coding
  ENST00000357568 CAPN3-008 42359585-42411773 protein_coding
  ENST00000397163 CAPN3-009 42359587-42412316 protein_coding
  ENST00000397200 CAPN3-007 42402390-42412317 protein_coding
  ENST00000397204 CAPN3-012 42404831-42412315 protein_coding
  ENST00000466222 CAPN3-014 42408466-42412318 retained_intron
  ENST00000561817 CAPN3-013 42404798-42412317 protein_coding
  ENST00000562199 CAPN3-020 42409787-42411001 processed_transcript
  ENST00000564503 CAPN3-019 42408314-42411857 protein_coding
  ENST00000565173 CAPN3-016 42404827-42408636 retained_intron
  ENST00000565274 CAPN3-018 42405932-42411863 nonsense_mediated_decay
  ENST00000565559 CAPN3-017 42404867-42410911 protein_coding
  ENST00000567071 CAPN3-011 42402799-42409963 protein_coding
  ENST00000567817 CAPN3-021 42410588-42412308 nonsense_mediated_decay
  ENST00000568153 CAPN3-022 42410884-42412247 nonsense_mediated_decay
  ENST00000569136 CAPN3-015 42404780-42411942 protein_coding
  ENST00000569827 CAPN3-010 42402418-42411341 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastMuscleENST00000318023ENST00000337571ENST00000397163ENST00000466222ENST00000569136
Transcript ID Brain Breast Muscle
ENST00000318023 N/A N/A 38.936±0.00
ENST00000337571 19.044±7.96 N/A N/A
ENST00000397163 N/A 10.951±0.00 56.933±35.50
ENST00000466222 14.043±0.00 N/A N/A
ENST00000569136 23.442±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004QL CIL_0004QL_0002 CGP 15:42273233-42412318
CIL_0004QM CIL_0004QM_0002 CGP 15:42359500-42491123

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001896 IEA autolysis
GO:0003824 IDA catalytic activity
GO:0004198 IEA calcium-dependent cysteine-type endopeptidase activity
GO:0004871 TAS signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0006461 ISS protein complex assembly
GO:0006508 IEA proteolysis
GO:0006915 TAS apoptotic process
GO:0007165 TAS signal transduction
GO:0007517 TAS muscle organ development
GO:0008233 IDA peptidase activity
GO:0008234 TAS cysteine-type peptidase activity
GO:0008307 ISS structural constituent of muscle
GO:0014718 ISS positive regulation of satellite cell activation involved in skeletal muscle regeneration
GO:0014850 ISS response to muscle activity
GO:0030016 ISS myofibril
GO:0030018 ISS Z disc
GO:0030239 ISS myofibril assembly
GO:0030315 ISS T-tubule
GO:0031402 ISS sodium ion binding
GO:0031432 IPI titin binding
GO:0032947 ISS protein complex scaffold
GO:0033234 IDA negative regulation of protein sumoylation
GO:0043066 IMP negative regulation of apoptotic process
GO:0043122 IMP regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043234 ISS protein complex
GO:0045214 ISS sarcomere organization
GO:0045661 IEA regulation of myoblast differentiation
GO:0045862 ISS positive regulation of proteolysis
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046716 TAS muscle cell cellular homeostasis
GO:0050790 IDA regulation of catalytic activity
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051281 ISS positive regulation of release of sequestered calcium ion into cytosol
GO:0051592 ISS response to calcium ion
GO:0055103 IDA ligase regulator activity
GO:0061061 ISS muscle structure development
GO:0070315 IEA G1 to G0 transition involved in cell differentiation
GO:0071277 ISS cellular response to calcium ion
GO:0071472 ISS cellular response to salt stress
GO:0072657 ISS protein localization to membrane
GO:0097264 IDA self proteolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041864 capn3a calpain 3a, (p94) protein_coding Danio_rerio
ENSDARG00000043035 capn3b calpain 3b protein_coding Danio_rerio
ENSMUSG00000079110 Capn3 calpain 3 protein_coding Mus_musculus

Loading