C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphoglycerate dehydrogenase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000369409 PHGDH-001 ENSG00000092621 9606 + 1:119711887-119744215 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369409
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369409 7.472±0.00 20.082±0.00 6.040±0.00 50.334±31.16 31.677±30.83 10.278±7.57 1.347±0.71 22.356±5.14 17.711±9.82 6.262±4.58 1.142±0.60 37.130±27.27 18.872±7.74 47.525±17.53

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004617 TAS:IEA phosphoglycerate dehydrogenase activity
GO:0005829 TAS cytosol
GO:0006541 IEA glutamine metabolic process
GO:0006544 IEA glycine metabolic process
GO:0006563 IEA L-serine metabolic process
GO:0006564 TAS:IEA L-serine biosynthetic process
GO:0006566 IEA threonine metabolic process
GO:0007420 TAS brain development
GO:0008152 IEA metabolic process
GO:0008652 TAS cellular amino acid biosynthetic process
GO:0009055 TAS electron carrier activity
GO:0009448 IEA gamma-aminobutyric acid metabolic process
GO:0010468 IEA regulation of gene expression
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0019530 IEA taurine metabolic process
GO:0021510 IEA spinal cord development
GO:0021782 IEA glial cell development
GO:0021915 IEA neural tube development
GO:0022008 IEA neurogenesis
GO:0031175 IEA neuron projection development
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0070314 IEA G1 to G0 transition

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000065793 Phgdh-001 protein_coding Mus_musculus 0 1949
ENSMUST00000120430 AC118721.1-001 processed_pseudogene Mus_musculus 0 1875
ENSMUST00000178959 Gm7901-201 pseudogene Mus_musculus 0 1738
ENSMUST00000119183 Gm13337-001 processed_pseudogene Mus_musculus 0 1701
ENSMUST00000172364 Gm9252-001 processed_pseudogene Mus_musculus 0 1666
ENSMUST00000180647 Gm6756-001 processed_pseudogene Mus_musculus 0 1657
ENSMUST00000121036 Gm13730-001 processed_pseudogene Mus_musculus 0 1334
ENSMUST00000117850 Gm6024-001 processed_pseudogene Mus_musculus 0 1306
ENSMUST00000118988 Gm5385-001 processed_pseudogene Mus_musculus 0 1297
ENSMUST00000183069 Gm8793-001 processed_pseudogene Mus_musculus 0 1133
ENSMUST00000153694 Phgdh-003 retained_intron Mus_musculus 0 549
ENSMUST00000148488 Phgdh-002 protein_coding Mus_musculus 0 494

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