C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: desmoplakin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000096696 DSP 9606 + 6:7541575-7586717 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000379802 DSP-001 7541575-7586717 protein_coding
  ENST00000418664 DSP-002 7541617-7586572 protein_coding
  ENST00000506617 DSP-007 7559286-7565817 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379802ENST00000418664
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379802 2.029±0.00 1.523±0.00 5.676±0.00 0.703±0.15 6.228±1.94 9.006±6.89 38.793±27.34 8.843±1.07 3.949±1.15 4.071±0.79 0.094±0.04 18.391±18.51 21.175±11.85 1.308±0.77
ENST00000418664 0.957±0.00 1.097±0.00 2.407±0.00 0.451±0.00 5.712±2.04 6.646±1.90 25.533±0.00 5.930±1.61 3.819±3.24 3.427±0.00 0.201±0.00 4.314±2.83 12.975±2.38 0.364±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007T6 CIL_0007T6_0001 VISTA 6:7260927-7862502
CIL_00037Y CIL_00037Y_0001 CGP 6:7389496-7586717
CIL_00037Z CIL_00037Z_0001 CGP 6:7541575-7611967

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001533 IDA cornified envelope
GO:0002934 ISS desmosome organization
GO:0003223 ISS ventricular compact myocardium morphogenesis
GO:0005080 IPI protein kinase C binding
GO:0005198 IDA structural molecule activity
GO:0005200 TAS structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005739 IEA mitochondrion
GO:0005856 IEA cytoskeleton
GO:0005882 ISS intermediate filament
GO:0005886 IDA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005916 IEA fascia adherens
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008544 TAS epidermis development
GO:0014704 IDA intercalated disc
GO:0016323 IEA basolateral plasma membrane
GO:0016337 IEA single organismal cell-cell adhesion
GO:0018149 IDA peptide cross-linking
GO:0030057 IEA desmosome
GO:0030216 IDA keratinocyte differentiation
GO:0030674 IDA protein binding, bridging
GO:0034332 IEA adherens junction organization
GO:0042060 IEA wound healing
GO:0043588 IEA skin development
GO:0044822 IDA poly(A) RNA binding
GO:0045104 IEA intermediate filament cytoskeleton organization
GO:0045109 ISS intermediate filament organization
GO:0050839 IEA cell adhesion molecule binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071896 ISS protein localization to adherens junction
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:0086069 IMP bundle of His cell to Purkinje myocyte communication
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:0097110 IPI scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022309 dspa desmoplakin a protein_coding Danio_rerio
ENSDARG00000076673 DSP (2 of 2) desmoplakin protein_coding Danio_rerio
ENSMUSG00000054889 Dsp desmoplakin protein_coding Mus_musculus

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