C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: desmoplakin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054889 Dsp 10090 + 13:38151328-38198577 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000124830 Dsp-001 38151348-38198577 protein_coding
  ENSMUST00000127906 Dsp-002 38151328-38198577 protein_coding
  ENSMUST00000145151 Dsp-003 38178367-38182234 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000124830ENSMUST00000127906
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000124830 0.623±0.43 0.089±0.04 5.527±0.84 0.306±0.07 0.565±0.23 8.203±1.41 25.617±2.69 1.193±0.06 1.446±0.43 3.550±1.86 0.078±0.00 3.918±4.18 29.269±20.46 0.063±0.00
ENSMUST00000127906 0.970±0.92 0.384±0.18 3.066±0.29 0.364±0.23 1.932±0.73 19.123±1.94 24.306±1.07 1.201±0.52 1.331±0.79 4.751±1.76 0.050±0.06 3.387±2.07 19.093±11.91 0.211±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000817 CIL_000817_0002 VISTA 13:37577817-38179534
CIL_0007T6 CIL_0007T6_0002 VISTA 13:37870525-38472280
CIL_00037Y CIL_00037Y_0002 CGP 13:38036989-38198577
CIL_00037Z CIL_00037Z_0002 CGP 13:38151328-38227663

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001533 IEA cornified envelope
GO:0002934 IMP desmosome organization
GO:0003223 IMP ventricular compact myocardium morphogenesis
GO:0005080 IEA protein kinase C binding
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005856 IEA cytoskeleton
GO:0005882 IDA intermediate filament
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005916 IEA fascia adherens
GO:0014704 IDA intercalated disc
GO:0016020 ISO membrane
GO:0016323 IDA basolateral plasma membrane
GO:0016337 IMP single organismal cell-cell adhesion
GO:0018149 IEA peptide cross-linking
GO:0030057 IDA desmosome
GO:0030216 IEA keratinocyte differentiation
GO:0030674 IEA protein binding, bridging
GO:0034332 IMP adherens junction organization
GO:0042060 IEA wound healing
GO:0043588 IMP skin development
GO:0044822 IEA poly(A) RNA binding
GO:0045104 IMP intermediate filament cytoskeleton organization
GO:0045109 IMP intermediate filament organization
GO:0050839 IEA cell adhesion molecule binding
GO:0070062 IEA extracellular vesicular exosome
GO:0071896 IMP protein localization to adherens junction
GO:0086005 IEA ventricular cardiac muscle cell action potential
GO:0086069 IEA bundle of His cell to Purkinje myocyte communication
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:0097110 IEA scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022309 dspa desmoplakin a protein_coding Danio_rerio
ENSDARG00000076673 DSP (2 of 2) desmoplakin protein_coding Danio_rerio
ENSG00000096696 DSP desmoplakin protein_coding Homo_sapiens

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