C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000099785 MARCH2 9606 + 19:8413270-8439017 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000215555 MARCH2-201 8413303-8439011 protein_coding
  ENST00000381035 MARCH2-002 8413270-8439004 protein_coding
  ENST00000594796 MARCH2-007 8421927-8430892 retained_intron
  ENST00000595142 MARCH2-003 8413290-8426668 protein_coding
  ENST00000595213 MARCH2-004 8413422-8422009 protein_coding
  ENST00000601283 MARCH2-005 8413305-8438731 protein_coding
  ENST00000601724 MARCH2-006 8413295-8426673 protein_coding
  ENST00000602117 MARCH2-001 8418405-8439017 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000215555ENST00000381035ENST00000594796ENST00000601283ENST00000602117
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000215555 36.944±0.00 20.723±0.00 N/A 28.154±22.38 37.013±33.45 26.853±25.45 22.199±18.29 13.152±0.00 9.040±7.57 14.697±13.81 20.344±15.65 10.755±5.62 22.809±9.41 13.456±10.39
ENST00000381035 N/A N/A N/A N/A N/A 0.485±0.00 N/A N/A N/A 0.587±0.00 N/A N/A N/A N/A
ENST00000594796 28.619±0.00 28.756±0.00 3.966±0.00 N/A 23.647±21.76 3.536±0.00 N/A 3.829±0.00 3.510±0.00 N/A 3.157±0.00 1.423±0.00 N/A N/A
ENST00000601283 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.212±0.00 N/A N/A
ENST00000602117 N/A N/A N/A 1.266±0.00 N/A N/A N/A 2.316±0.00 N/A N/A N/A 1.128±0.00 4.492±0.00 1.037±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NQ CIL_0002NQ_0001 CGP 19:7926718-8445041
CIL_0000UT CIL_0000UT_0001 CGP 19:7958579-8445041
CIL_0005GY CIL_0005GY_0002 CGP 19:8413270-8489114

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0005764 IEA lysosome
GO:0005768 IEA endosome
GO:0005783 IDA endoplasmic reticulum
GO:0006897 IEA endocytosis
GO:0008270 IEA zinc ion binding
GO:0016021 IEA integral component of membrane
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031410 IDA cytoplasmic vesicle
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061738 march2 membrane-associated ring finger (C3HC4) 2 protein_coding Danio_rerio
ENSMUSG00000079557 March2 membrane-associated ring finger (C3HC4) 2 protein_coding Mus_musculus

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