C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: topoisomerase (DNA) III beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100038 TOP3B 9606 - 22:21957025-21982816 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357179 TOP3B-001 21957025-21982816 protein_coding
  ENST00000398793 TOP3B-003 21957031-21982750 protein_coding
  ENST00000424393 TOP3B-012 21968619-21982780 protein_coding
  ENST00000430142 TOP3B-007 21971897-21982813 protein_coding
  ENST00000434517 TOP3B-008 21975646-21982773 protein_coding
  ENST00000436282 TOP3B-005 21957032-21967650 nonsense_mediated_decay
  ENST00000437103 TOP3B-010 21974433-21982793 protein_coding
  ENST00000437929 TOP3B-013 21971895-21982766 protein_coding
  ENST00000442653 TOP3B-014 21974419-21975969 protein_coding
  ENST00000444502 TOP3B-002 21957031-21982790 nonsense_mediated_decay
  ENST00000449704 TOP3B-011 21974379-21982787 protein_coding
  ENST00000456075 TOP3B-009 21974376-21982766 protein_coding
  ENST00000457179 TOP3B-004 21957027-21982790 nonsense_mediated_decay
  ENST00000457270 TOP3B-006 21957027-21968740 protein_coding
  ENST00000470338 TOP3B-017 21962128-21962895 retained_intron
  ENST00000487485 TOP3B-016 21970335-21971632 retained_intron
  ENST00000489581 TOP3B-015 21972219-21975796 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastColonKidneyMuscleOvaryTestisENST00000357179ENST00000424393ENST00000457179
Transcript ID Bladder Breast Colon Kidney Muscle Ovary Testis
ENST00000357179 1.038±0.00 1.305±0.00 1.685±0.00 3.747±0.00 2.115±1.69 3.779±2.22 2.514±0.58
ENST00000424393 N/A N/A N/A N/A 1.538±0.00 N/A N/A
ENST00000457179 N/A N/A N/A N/A N/A 4.295±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003KY CIL_0003KY_0002 CGP 22:21919420-21982816

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000793 IEA condensed chromosome
GO:0003677 IEA DNA binding
GO:0003916 TAS:IEA DNA topoisomerase activity
GO:0003917 IEA DNA topoisomerase type I activity
GO:0005634 IDA nucleus
GO:0006265 IEA DNA topological change
GO:0007059 IEA chromosome segregation
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027586 top3b topoisomerase (DNA) III beta protein_coding Danio_rerio
ENSMUSG00000022779 Top3b topoisomerase (DNA) III beta protein_coding Mus_musculus

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