C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: topoisomerase (DNA) III beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022779 Top3b 10090 + 16:16870736-16892990 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023465 Top3b-001 16870781-16892990 protein_coding
  ENSMUST00000118424 Top3b-007 16870786-16885465 retained_intron
  ENSMUST00000119787 Top3b-004 16870757-16892985 protein_coding
  ENSMUST00000124185 Top3b-012 16890226-16892500 protein_coding
  ENSMUST00000124960 Top3b-017 16870787-16880649 protein_coding
  ENSMUST00000125202 Top3b-005 16870965-16879467 retained_intron
  ENSMUST00000128407 Top3b-015 16887839-16892975 retained_intron
  ENSMUST00000128497 Top3b-010 16886644-16887710 retained_intron
  ENSMUST00000129969 Top3b-016 16886910-16887887 retained_intron
  ENSMUST00000130650 Top3b-014 16870767-16879325 protein_coding
  ENSMUST00000131063 Top3b-019 16870840-16878987 protein_coding
  ENSMUST00000135597 Top3b-002 16870817-16892990 retained_intron
  ENSMUST00000138618 Top3b-006 16870800-16879340 retained_intron
  ENSMUST00000139740 Top3b-003 16870736-16885849 protein_coding
  ENSMUST00000144513 Top3b-018 16870807-16879052 protein_coding
  ENSMUST00000147531 Top3b-009 16885526-16886706 retained_intron
  ENSMUST00000150424 Top3b-008 16884212-16892990 retained_intron
  ENSMUST00000151271 Top3b-013 16891502-16892419 retained_intron
  ENSMUST00000156502 Top3b-020 16870774-16883526 protein_coding
  ENSMUST00000156951 Top3b-021 16883442-16892973 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023465ENSMUST00000118424ENSMUST00000119787ENSMUST00000128407ENSMUST00000135597ENSMUST00000139740ENSMUST00000150424
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023465 N/A 3.488±0.27 N/A N/A N/A N/A N/A N/A N/A 3.806±0.00 1.202±0.31 4.609±0.00 3.970±0.06 N/A
ENSMUST00000118424 5.591±0.17 3.036±0.00 4.705±0.99 0.795±0.00 4.993±0.32 4.462±0.00 1.700±0.00 N/A N/A 4.721±0.80 1.080±0.08 2.874±1.19 2.560±1.05 N/A
ENSMUST00000119787 N/A N/A N/A N/A N/A N/A 1.934±0.00 N/A 2.811±0.49 3.683±0.13 1.176±0.14 N/A N/A 8.496±0.46
ENSMUST00000128407 8.066±0.47 8.106±1.37 N/A 10.756±0.85 10.075±1.93 9.102±1.76 3.439±0.66 11.864±1.43 3.626±0.58 8.556±1.04 N/A 14.139±1.43 N/A N/A
ENSMUST00000135597 4.549±0.00 N/A 3.361±0.00 N/A 3.389±0.00 3.452±0.13 N/A N/A 2.515±0.09 N/A 0.885±0.00 N/A 3.651±0.04 N/A
ENSMUST00000139740 N/A N/A N/A 4.068±0.00 N/A N/A N/A N/A 9.943±0.44 N/A N/A N/A 6.870±0.45 17.214±0.00
ENSMUST00000150424 20.458±2.84 9.325±2.63 16.334±0.74 16.179±5.67 18.039±2.04 17.604±2.23 9.021±2.23 24.849±2.37 13.239±4.03 11.846±1.69 2.175±0.46 24.558±4.76 13.269±3.08 18.196±1.81

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PT CIL_0008PT_0002 VISTA 16:16870677-17470725

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000793 IDA condensed chromosome
GO:0003677 IEA DNA binding
GO:0003917 IEA DNA topoisomerase type I activity
GO:0005634 IEA nucleus
GO:0006265 IEA DNA topological change
GO:0007059 IMP chromosome segregation
GO:0044822 IEA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027586 top3b topoisomerase (DNA) III beta protein_coding Danio_rerio
ENSG00000100038 TOP3B topoisomerase (DNA) III beta protein_coding Homo_sapiens

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