C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TIMP metallopeptidase inhibitor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100234 TIMP3 9606 + 22:32801701-32863043 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000266085 TIMP3-001 32801701-32863043 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000266085
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000266085 716.689±0.00 280.857±0.00 26.124±0.00 28.417±18.74 172.480±119.52 128.068±104.14 91.585±65.69 136.103±127.96 45.463±16.45 412.504±283.37 33.756±19.04 34.864±19.83 1099.166±504.27 152.129±110.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NM CIL_0002NM_0001 CGP 22:32474676-33058372
CIL_0007RH CIL_0007RH_0001 VISTA 22:32494872-33098241
CIL_000337 CIL_000337_0001 CGP 22:32512552-33058372

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005604 IEA basement membrane
GO:0005634 IDA nucleus
GO:0007601 IEA visual perception
GO:0008191 TAS:IEA metalloendopeptidase inhibitor activity
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0031012 IDA extracellular matrix
GO:0046872 IEA metal ion binding
GO:0051045 IMP negative regulation of membrane protein ectodomain proteolysis
GO:0070062 IDA extracellular vesicular exosome
GO:0071310 IEA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000020044 Timp3 tissue inhibitor of metalloproteinase 3 protein_coding Mus_musculus

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