C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: THO complex 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100296 THOC5 9606 - 22:29505879-29555216 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358079 THOC5-005 29508331-29549157 nonsense_mediated_decay
  ENST00000397871 THOC5-201 29508168-29553655 protein_coding
  ENST00000397872 THOC5-202 29508168-29553655 protein_coding
  ENST00000397873 THOC5-004 29508358-29553766 protein_coding
  ENST00000414902 THOC5-012 29543429-29553741 nonsense_mediated_decay
  ENST00000418021 THOC5-009 29543503-29555216 protein_coding
  ENST00000428374 THOC5-008 29539444-29553680 protein_coding
  ENST00000440771 THOC5-010 29536667-29553655 protein_coding
  ENST00000442555 THOC5-002 29508327-29554254 nonsense_mediated_decay
  ENST00000443089 THOC5-015 29525838-29542888 protein_coding
  ENST00000455450 THOC5-013 29539338-29545144 protein_coding
  ENST00000472164 THOC5-017 29508329-29511442 retained_intron
  ENST00000475187 THOC5-007 29534538-29549144 retained_intron
  ENST00000484924 THOC5-016 29519006-29536738 retained_intron
  ENST00000488052 THOC5-014 29531553-29536738 retained_intron
  ENST00000490103 THOC5-001 29505879-29553782 protein_coding
  ENST00000492707 THOC5-003 29528383-29539469 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000358079ENST00000397871ENST00000397873ENST00000418021ENST00000428374ENST00000440771ENST00000443089ENST00000490103
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000358079 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.606±0.00 N/A N/A N/A
ENST00000397871 N/A 5.535±0.00 N/A 4.504±0.00 3.448±0.00 3.242±0.00 3.732±0.00 N/A N/A 6.137±0.00 6.366±1.62 5.133±1.00 6.535±0.00
ENST00000397873 6.861±0.00 4.798±0.00 N/A N/A 3.561±0.32 7.623±0.00 2.542±0.75 2.722±0.00 4.421±0.57 8.270±0.00 N/A 4.427±2.28 10.167±0.94
ENST00000418021 N/A N/A 21.095±0.00 N/A N/A N/A N/A N/A N/A N/A 18.813±0.00 N/A 32.505±0.00
ENST00000428374 N/A N/A 7.709±0.00 N/A N/A N/A 5.872±0.00 7.551±0.00 N/A 9.212±0.00 N/A N/A N/A
ENST00000440771 N/A N/A N/A N/A 3.517±0.00 4.090±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000443089 N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.204±0.00 N/A N/A N/A
ENST00000490103 N/A N/A N/A 1.743±0.00 0.857±0.00 N/A 0.654±0.00 0.761±0.00 0.722±0.00 1.131±0.29 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000346 IDA transcription export complex
GO:0000347 IDA THO complex
GO:0000445 IDA THO complex part of transcription export complex
GO:0000902 IEA cell morphogenesis
GO:0001824 IEA blastocyst development
GO:0003729 IEA mRNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006397 IEA mRNA processing
GO:0006406 IDA mRNA export from nucleus
GO:0008380 IEA RNA splicing
GO:0010468 IEA regulation of gene expression
GO:0010793 IEA regulation of mRNA export from nucleus
GO:0017145 IEA stem cell division
GO:0030224 IDA monocyte differentiation
GO:0032786 IMP positive regulation of DNA-templated transcription, elongation
GO:0045650 IEA negative regulation of macrophage differentiation
GO:0046784 IDA viral mRNA export from host cell nucleus
GO:0060215 ISS primitive hemopoiesis
GO:2000002 IMP negative regulation of DNA damage checkpoint
GO:2000035 IEA regulation of stem cell division

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038290 thoc5 THO complex 5 protein_coding Danio_rerio
ENSMUSG00000034274 Thoc5 THO complex 5 protein_coding Mus_musculus

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