C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho GTPase activating protein 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100852 ARHGAP5 9606 + 14:32076114-32159728 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216743 ARHGAP5-005 32154010-32157216 retained_intron
  ENST00000345122 ARHGAP5-201 32077289-32159728 protein_coding
  ENST00000396582 ARHGAP5-003 32077074-32159728 protein_coding
  ENST00000432921 ARHGAP5-202 32077289-32155138 protein_coding
  ENST00000433497 ARHGAP5-004 32077309-32157079 protein_coding
  ENST00000539826 ARHGAP5-001 32076985-32155083 protein_coding
  ENST00000554090 ARHGAP5-008 32078231-32154633 protein_coding
  ENST00000555814 ARHGAP5-006 32076114-32090780 protein_coding
  ENST00000556191 ARHGAP5-007 32078231-32091089 protein_coding
  ENST00000556611 ARHGAP5-002 32076967-32155011 protein_coding
  ENST00000557643 ARHGAP5-009 32094038-32154827 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216743ENST00000345122ENST00000396582ENST00000433497ENST00000539826ENST00000556191ENST00000556611
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216743 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.260±0.00 N/A
ENST00000345122 N/A 2.036±0.00 1.804±0.00 8.391±0.90 3.301±0.37 2.457±0.24 2.066±0.23 4.664±0.00 2.097±1.71 4.016±0.73 0.644±0.04 4.274±1.30 1.383±0.78 4.114±2.22
ENST00000396582 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.862±0.00 N/A
ENST00000433497 4.611±0.00 3.834±0.00 N/A 9.291±0.00 5.387±0.00 7.936±0.00 5.751±0.00 13.236±0.00 1.542±0.00 4.603±0.00 2.034±0.00 4.450±0.00 2.205±0.00 11.395±0.00
ENST00000539826 N/A N/A 7.618±0.00 6.821±0.00 10.083±0.00 6.806±0.00 6.363±0.00 3.135±0.00 7.785±7.10 10.416±0.00 2.496±0.71 22.515±0.00 1.703±0.58 6.149±0.00
ENST00000556191 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.471±0.00
ENST00000556611 3.722±0.00 N/A 3.266±0.00 7.996±0.00 4.623±0.00 3.866±0.00 N/A 4.008±0.00 N/A N/A N/A 3.147±1.17 1.428±0.00 3.641±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005RC CIL_0005RC_0002 CGP 14:31489956-32159728
CIL_0000H7 CIL_0000H7_0001 CGP 14:32076114-32837681

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002053 IEA positive regulation of mesenchymal cell proliferation
GO:0003924 TAS GTPase activity
GO:0005100 TAS Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006184 TAS GTP catabolic process
GO:0007155 TAS cell adhesion
GO:0007165 IEA signal transduction
GO:0007264 TAS:IEA small GTPase mediated signal transduction
GO:0007266 TAS Rho protein signal transduction
GO:0008361 IEA regulation of cell size
GO:0016020 IEA membrane
GO:0030335 IEA positive regulation of cell migration
GO:0030879 IEA mammary gland development
GO:0032321 TAS positive regulation of Rho GTPase activity
GO:0042169 IPI SH2 domain binding
GO:0051056 TAS regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061294 arhgap5 Rho GTPase activating protein 5 protein_coding Danio_rerio
ENSMUSG00000035133 Arhgap5 Rho GTPase activating protein 5 protein_coding Mus_musculus

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